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Background:
The increase in food intolerances poses a burgeoning problem in our society. Food intolerances not only lead to physical impairment of the individual patient but also result in a high socio-economic burden due to factors such as the treatment required as well as absenteeism. The present study aimed to explore whether lactose intolerant (LI) patients exhibit more frequent comorbidities than non-LI patients.
Methods:
The study was conducted on a case-control basis and the results were determined using routine data analysis. Routine data from the IMS Disease Analyzer database were used for this purpose. A total of 6,758 data records were processed and analyzed.
Results:
There were significant correlations between LI and the incidence of osteoporosis, changes in mental status, and the presence of additional food intolerances. Comparing 3,379 LI vs. 3,379 non-LI patients, 34.5% vs. 17.7% (P<0.0001) suffered from abdominal pain; 30.6% vs. 17.2% (P<0.0001) from gastrointestinal infections; and 20.9% vs. 16.0% (P=0.0053) from depression. Adjusted odds ratios (OR) were the highest for fructose intolerance (n=229 LI vs. n=7 non-LI; OR 31.06; P<0.0001), irritable bowel syndrome (n=247 LI vs. n=44 non-LI; OR 5.23; P<0.0001), and bloating (n=351 LI vs. n=68 non-LI; OR 4.94; P<0.0001).
Conclusion:
The study confirms that LI should not be regarded as an isolated illness but considered a possible trigger for further diseases. Additional research is necessary to assert more precise statements.
According to the third-person effect or the influence of presumed media influence approach, the presumption that the media has strong effects on other people can affect individuals’ attitudes and behavior. For instance, if people believe in strong media influences on others, they are more likely to increase their communication activities or support demands for restrictions on media. A standardized online survey among German journalists (N = 960) revealed that the stronger the journalists perceive the political online influence on the public to be, the more frequently they contradict unwanted political views in their articles. Moreover, even journalists are more likely to approve of restrictions on the Internet’s political influence, the stronger they believe the effects of online media to be. The data reveal no connections between communication activities and demands for restrictions.
Research question: Rivalries in team sports are commonly conceptualized as a threat to the fans’ identity. Therefore, past research has mainly focused on the negative consequences. However, theoretical arguments and empirical evidence suggest that rivalry has both negative and positive effects on fans’ self-concept. This research develops and empirically tests a model which captures and integrates these dual effects of rivalry.
Research methods: Data were collected via an on-site survey at home games of eight German Bundesliga football teams (N = 571). Structural equation modeling provides strong support for the proposed model.
Results and findings: In line with previous research, the results show that rivalry threatens fans’ identity as reflected in lower public collective self-esteem in relation to supporters of the rival team. However, the results also show that there are crucial positive consequences, such as higher perceptions of public collective self-esteem in relation to supporters of non-rival opponents, perceived ingroup distinctiveness and ingroup cohesion. These positive effects are mediated through increases in disidentification with the rival and perceived reciprocity of rivalry.
Implications: We contribute to the literature by providing a more balanced view of one of team sports’ key phenomena. Our results indicate that the prevalent conceptualization of rivalry as an identity threat should be amended by the positive consequences. Our research also offers guidance for the promotion of rivalries, where the managerial focus should be on creating a perception that a rivalry is reciprocal.
Surface atomic relaxation and magnetism on hydrogen-adsorbed Fe(110) surfaces from first principles
(2016)
We have computed adsorption energies, vibrational frequencies, surface relaxation and buckling for hydrogen adsorbed on a body-centred-cubic Fe(110) surface as a function of the degree of H coverage. This adsorption system is important in a variety of technological processes such as the hydrogen embrittlement in ferritic steels, which motivated this work, and the Haber–Bosch process. We employed spin-polarised density functional theory to optimise geometries of a six-layer Fe slab, followed by frozen mode finite displacement phonon calculations to compute Fe–H vibrational frequencies. We have found that the quasi-threefold (3f) site is the most stable adsorption site, with adsorption energies of ∼3.0 eV/H for all coverages studied. The long-bridge (lb) site, which is close in energy to the 3f site, is actually a transition state leading to the stable 3f site. The calculated harmonic vibrational frequencies collectively span from 730 to 1220 cm−1, for a range of coverages. The increased first-to-second layer spacing in the presence of adsorbed hydrogen, and the pronounced buckling observed in the Fe surface layer, may facilitate the diffusion of hydrogen atoms into the bulk, and therefore impact the early stages of hydrogen embrittlement in steels.
The ability to functionalize graphene with several methods, such as radical reactions, cycloadditions, hydrogenation, and oxidations, allows this material to be used in a large range of applications. In this framework, it is essential to be able to control the efficiency and stability of the functionalization process—this requires understanding how the graphene reactivity is affected by the environment, including the substrate. In this work we provide an insight on the substrate dependence of graphene reactivity towards hydrogenation by comparing three different substrates: silicon, hexagonal boron nitride (h-BN), and molybdenum disulfide (MoS2). Although MoS2 and h-BN have flatter surfaces than silicon, we found that the H coverage of graphene on h-BN is about half of the H coverage on graphene on both silicon and MoS2. Therefore, graphene shows strongly reduced reactivity towards hydrogenation when placed on h-BN. The difference in hydrogenation reactivity between h-BN and MoS2 may indicate a stronger van der Waals force between graphene and h-BN, compared to MoS2, or may be related to the chemical properties of MoS2, which is a well-known catalyst for hydrogen evolution reactions.
At University of Applied Sciences and Arts Hannover, LON-CAPA is used as a learning management system beside Moodle. LON-CAPA has a strong focus on e-assessment in mathematics and sciences. We used LON-CAPA in Hannover mainly in mathematics courses.
Since theoretical computer science needs a lot of mathematics, this course is also well-suited for e-assessment in LON-CAPA. Beside this, we already used JFLAP as an interactive tool to deal with automata, machines and grammars in theoretical computer science. In LON-CAPA, there exists a possibility of using external graders to grade problems.
We decided to write a grading engine (with JFLAP inside) to grade automata, machines and grammars handed in by students and to couple this with LON-CAPA. This report describes the types of questions that are now possible with this grader and how they can be authored in LON-CAPA.
Industrial Control Systems (ICS) succumb to an ever evolving variety of threats. Additionally, threats are increasing in number and get more complex. This requires a holistic and up-to-date security concept for ICS as a whole. Usually security concepts are applied and updated based on regularly performed ICS security assessments. Such ICS security assessments require high effort and extensive knowledge about ICS and its security. This is often a problem for small and mediumsized enterprises (SME), which do not have sufficient respective sufficiently skilled human resources. This paper defines in a first step requirements on the knowledge needed to perform an ICS security assessment and the life cycle of this knowledge. Afterwards the ICS security knowledge and its life cycle are developed and discussed considering the requirements and related work.
Bedingt durch die zunehmende Digitalisierung der wissenschaftlichen Ausbildung entstanden verschiedenste Lehrplattformen, mit denen die Verwaltung von Lehrveranstaltungen und Lehrmitteln möglich geworden ist. Die Plattform LON-CAPA ist eine davon.
Neben der Verwaltung von Lehrveranstaltungen konnten innerhalb der Plattform über eine Programmierschnittstelle auch Übungsaufgaben definiert werden, die durch das Hinterlegen der korrekten Antwort oder bei der Definition von Multiple-Choice Aufgaben einem Studierenden automatisch Feedback über dessen Lösung geben können. Komplexere Aufgaben mussten dagegen häufig manuell durch Menschen korrigiert werden.
Für die formalen Sprachen und die Automatenlehre der theoretischen Informatik wurde daher die in Java geschriebene Bibliothek JFLAP modifiziert, um als Bewertungsinstrument Aufgaben aus diesem Themengebiet automatisch auf Korrektheit bewerten zu können. Ein genereller Interfaceansatz ermöglich zusätzliche eine zugängliche Definition weiterer Aufgaben für die untersuchten Themengebiete.
Im Rahmen des vom Bundesministerium für Wirtschaft und Technologie geförderten Forschungsprojektes INSA sollen wichtige Beiträge zur Verbesserung der IT-Sicherheit von Produktionsanlagen insbesondere in kleinen und mittelständischen Unternehmen (KMU) realisiert und erprobt werden.
Die IT-Sicherheit von Produktionsanlagen wird zu einer immer wichtigeren Komponente des Schutzes von Unternehmen gegen Cyber-Attacken. Neben Angriffen aus dem Internet sind dabei interne Angriffsquellen in Betracht zu ziehen. Gängige Vorgehensmodelle, wie z. B. die VDI-Richtlinie 2182, setzen dabei unter anderem auf eine wiederkehrende Analyse der Bedrohungen und auf die Implementierung entsprechender Schutzmaßnahmen. Die Durchführung einer solchen wiederkehrenden Gefährdungsanalyse ist mit einem wiederkehrenden manuellen Aufwand verbunden, weshalb kleine und mittlere Unternehmen die Durchführung dieser Maßnahmen häufig meiden. Ziel des Projektes ist die Unterstützung kleiner und mittlerer Unternehmen bei der Durchführung entsprechender Bedrohungsanalysen zu unterstützen.
Der Ansatz des Projektes beruht auf der automatisierten bzw. teilautomatisierten Erfassung der installierten Automatisierungskomponenten (Assets). Danach kann für bekannte Standardkomponenten durch die Verwendung wissensbasierter Methoden eine Beurteilung der Bedrohung einer Automatisierungsanlage erfolgen. Hierfür wird fachspezifisches Wissen erfasst und verarbeitet wird. Diese Methoden können bei Bedarf in die Engineering-Oberfläche einer Automatisierungsanlage intergiert werden.
Das ProFormA-Aufgabenformat wurde eingeführt, um den Austausch von Programmieraufgaben zwischen beliebigen Autobewertern (Grader) zu ermöglichen. Ein Autobewerter führt im ProFormA-Aufgabenformat spezifizierte „Tests“ sequentiell aus, um ein vom Studierenden eingereichtes Programm zu prüfen. Für die Strukturierung und Darstellung der Testergebnisse existiert derzeit kein graderübergreifender Standard. Wir schlagen eine Erweiterung des ProFormA-Aufgabenformats um eine Hierarchie von Bewertungsaspekten vor, die nach didaktischen Aspekten gruppiert ist und entsprechende Testausführungen referenziert. Die Erweiterung wurde in Graja umgesetzt, einem Autobewerter für Java-Programme. Je nach gewünschter Detaillierung der Bewertungsaspekte sind Testausführungen in Teilausführungen aufzubrechen. Wir illustrieren unseren Vorschlag mit den Testwerkzeugen Compiler, dynamischer Softwaretest, statische Analyse sowie unter Einsatz menschlicher Bewerter.