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Klimt artwork: red-pigment material investigation by backscattering Fe-57 Mössbauer spectroscopy, SEM and p-XRF (2017)

Lehmann, R. ; Wengerowsky, D. ; Schmidt, H.J. ; Kumar, M. ; Niebur, A. ; Costa, B.F.O. ; Dencker, F. ; Klingelhöfer, G. ; Sindelar, Ralf Franz ; Renz, F.

Material tests were performed on a rediscovered Klimt-artwork “Trompetender Putto”. We performed studies on the red colored spots, mainly taken from non-restored parts. MIMOS II Fe-57 Mössbauer spectroscopy (novelty in art-pigment analysis) mainly reveals haematite and crystallized goethite in red colors. Electron microscopy can identify various layers of the original and overpainting of an artwork. The number of layers fluctuates between three and four chemically painted areas. The portable X-ray fluorescence analysis enables to reduce the pigment list to containing mercury (cinnabar), lead, zinc, iron and titanium. Infrared-lightirradiation visualizes the different age of the pigments.

Dry Period or Early Lactation — Time of Onset and Associated Risk Factors for Intramammary Infections in Dairy Cows (2021)

Nitz, Julia ; Wente, Nicole ; Zhang, Yanchao ; Klocke, Doris ; tho Seeth, Martin ; Krömker, Volker

The aim of this study was to define the time-related period of intramammary infections and its relation to risk factors for intramammary infections and clinical mastitis at cow and quarter levels. In total, 269 German Holstein Frisian dairy cows on three farms in Northern and Eastern Germany were included in this study. Quarter milk samples were collected at dry-off, 3 ± 1 days after calving and 17 ± 3 days after calving, for cytomicrobiological examination. Risk factors at quarter- and cow-level associated with intramammary infections and clinical mastitis were recorded during the trial period. Data were analyzed using logistic regression procedures and odds ratios were calculated. Calving for the second time increased the odds of clinical mastitis during the first 100 days of lactation compared to cows calving for the third time or more. A high milk yield after calving was a risk factor for new infections, with environmental pathogens 17 ± 3 days postpartum. A body condition score after calving less than 3.5 was associated with a decreased risk of having an intra-mammary infection (IMI) with non-aureus staphylococci and coryneforms 3 ± 1 days postpartum and consistent body condition between dry-off and early lactation decreased the risk of intramammary infections after calving. The absence of a ring of hyperkeratosis at the teat apex shown at dry-off was associated with a lower risk of intramammary infections with environmental pathogens 17 ± 3 days postpartum. This study shows the important influence of the dry period and early lactation on intramammary infections and clinical mastitis postpartum in dairy cows. Udder quarters may have eliminated pathogens during the dry period in 43.6% of cases in this study. Additionally, new infections occurred during early lactation, so 5.1% more quarters were infected 17 ± 3 days compared to 3 ± 1 days postpartum. New infections can be traced to non-aureus staphylococci and Staphylococcus aureus from dry-off up until 3 ± 1 days postpartum, and to non-aureus staphylococci, Staphylococcus aureus and Streptococcus uberis, after calving. In total, 88.7% of the infected quarters showed new infections with another pathogen species 3 ± 1 days postpartum than at dry-off, and 89.2% of the quarters 17 ± 3 days postpartum than 3 ± 1 days postpartum. In conclusion, the early lactation has just as important an influence on intramammary infections postpartum in dairy cows as the dry period. There is the possibility that udder quarters eliminate pathogens during the early lactation, especially during the dry period. However, there is also the danger that new infections manifest, with a large proportion of new infections occurring after calving. Thus, additional control strategies are of great importance to prevent new infections occurring during early lactation as well as during the dry period to reduce negative effects on milk yield and culling hazards in dairy cows by minimizing the associated risk factors

Ein System zur Lernunterstützung und Bewertung für die relationale Algebra (2021)

Shmit, Firas

In dieser Arbeit wurde ein System entwickelt, welches Übungsaufgaben der relationalen Algebra automatisch auswertet und dies in Form einer Punktevergabe bewertet. Darüber hinaus ist das System in der Lage lernunterstützende Feedbacks zu generieren. Dadurch sollen Studierende, die im Rahmen der Datenbank-Vorlesung relationale Algebra lernen, eine korrekte und optimierte Sprachanwendung im Bereich der relationalen Algebra lernen.

Konzeptionelle und praktische Überlegungen zu einer gesundheitsfördernden Fakultät - Ein Manual für den hochschulischen Transfer - Campus Kleefeld (2021)

Bonse-Rohmann, Mathias ; Brähler, Niklas ; Köhler, Annika ; Meißner, Pia ; Myrach, Maria-Luisa ; Rabenberg, Claudia ; Ritter, Sarah ; Sting, Anna-Lena ; Weiner, Ruven

Mehr als 3,5 Millionen Menschen verbringen an deutschen Hochschulen den Großteil ihres Tages und sind hier gesundheitlichen Belastungen ausgesetzt. Die Rahmenbedingungen an Hochschulen können erheblichen Einfluss auf die Gesundheit der Studierenden und Beschäftigten haben. Die soziale Verantwortung der Fakultät V gegenüber den dort Studierenden und Beschäftigten hat zur Initiierung des Projektes der „Gesundheitsfördernden Fakultät V – Campus Kleefeld“ geführt. Das Projekt zielt auf den Erhalt bzw. die nachhaltige Förderung der Gesundheit und Gesundheitskompetenz der dort lokalisierten Statusgruppen ab und möchte damit insbesondere die Motivation und Zufriedenheit der Studierenden und Beschäftigten an der Fakultät V unterstützen. Dieses Handbuch richtet sich an Fakultäten, die Interesse an einer langfristigen und nachhaltigen Implementierung gesundheitsförderlicher Maßnahmen für Studierende und/oder Beschäftigte haben und nach einer greifbaren sowie praxisnahen Unterstützung suchen.

A Comparison of healthy people 2020 – LHI topics between student populations within the USA, Germany, and Poland (2021)

Kaczmarek-Sondej, Wiktoria

As noted by Roman poet Virgil already more than 2,000 years ago: “The greatest wealth is health.”. Without health, there is no happiness, no peace, and no success according to the Reflections Recovery Center from Arizona, United States (USA, U.S.). The goal of the Healthy People 2020-project (HP2020), which is led by the Office of Disease Prevention and Health Promotion (ODPHP), was to “promote quality life, healthy development, and health behaviors across all life stages” among the U.S. population. HP2020 measures progress by using so-called Leading Health Indicators (LHI), reliable data sources, baseline values as well as targets for LHI-individual improvements for every measurable objective to be achieved by 2020 and each following decade. In the further course, these values were compared to student populations from the U.S., Germany, and Poland. The goal of this master's thesis was to obtain more data on international health, particularly among student populations. For the statistical analysis, data were obtained from an online survey that was distributed to students in at least one university in each of the three countries. In total, data from 380 students were analyzed in terms of HP2020 goal attainment. To determine if statistically significant differences were present, the z-test was used. The biggest differences emerged on the following topics: access to healthcare, environmental quality, obesity as well as reproductive and sexual health.

Evolutionäre Algorithmen - Genetische Algorithmen zur Musikkomposition (2021)

Elsner, Evelyn

Die Bachelorarbeit befasst sich mit dem Generieren kurzer fröhlicher und harmonischer Musikstücke mittels des Einsatzes genetischer Algorithmen. Dabei werden die Evolutionsprozesse der Biologie nachgeahmt. In der Programmiersprache Java, unter der Verwendung der Open-Source-Programmierbibliothek JFugue, sind dafür die einzelnen Zyklusphasen entworfen und implementiert worden. Die Vereinigung der Biologie, der Kunst und der Informatik wird damit erreicht, um etwas ästhetisch Wirksames zu schaffen und stellt den besonderen Reiz der Arbeit dar.

Finanzierung und Förderung Digitaler Bildung in Öffentlichen Bibliotheken : Deutsche Bibliotheksgesetze und Alternativen im Vergleich (2021)

Freimann, Janina

Öffentliche Bibliotheken sind in der Digitalen Bildung von großer Bedeutung. Sie vermitteln digitale Kompetenzen, nutzen zunehmend neue Technologien und verleihen digitale Medien. Die Arbeit befasst sich mit der Förderung und Finanzierung digitaler Angebote in Bibliotheken. Zu Beginn wird ein Überblick über die Bibliotheksgesetzgebung in Deutschland gegeben. In diesem Zusammenhang wird die Forderung der Bibliotheken nach einer Normierung zur Pflichtaufgabe für Kommunen erörtert und ein Vergleich mit den europäischen Ländern Dänemark und Finnland gezogen. Eine Untersuchung der Drittmittelförderung auf Landesebene, Bundesebene und der Europäischen Kommission zeigt die Verortung der Bibliotheken in Förderprogrammen auf. Im Anschluss werden anhand von Best-Practice-Beispielen alternative Finanzierungsmöglichkeiten dargestellt. Meinungen von Vertretern aus Bibliotheken weisen auf die Vorteile und Nachteile von Drittmittelförderung, Fundraising, Rechtsformwechsel, Integration in die Stadtentwicklung oder die Entwicklung von Bibliothekskonzeptionen, Bibliotheksentwicklungsplänen sowie die Regelung durch Kulturfördergesetze hin. Ausgehend von den Ergebnissen der untersuchten Finanzierungmöglichkeiten wird abschließend die Notwendigkeit von Bibliotheksgesetzen diskutiert. Hieraus ergibt sich, dass Bibliotheksgesetze für eine einheitliche und zukunftsfähige Entwicklung der Bibliotheken in der Digitalen Bildung notwendig sind. Zugleich wird deutlich, dass die derzeit bestehenden Gesetze diese Anforderungen nicht leisten.

Are Severe Mastitis Cases in Dairy Cows Associated with Bacteremia? (2021)

Brennecke, Julia ; Falkenberg, Ulrike ; Wente, Nicole ; Krömker, Volker

The objective of this study was to investigate the occurrence of bacteremia in dairy cows with severe mastitis. Milk samples were collected from affected udder quarters, and corresponding blood samples were collected from dairy cows with severe mastitis at the time of diagnosis before any therapeutic measures were undertaken. The cultural detection of pathogens in blood classified a bacteremia. Further diagnostic tests were performed to provide evidence of bacteremia. This was realized by PCR with regard to S. aureus, E. coli and S. uberis and the Limulus test. Detection of culturable pathogens in the blood of cows with severe clinical mastitis was rare and occurred in only one of 70 (1.4%) cases. Overall, bacterial growth was detected in 53 of 70 (75.7%) milk samples. S. uberis (22/70), E. coli (12/70) and S. aureus (4/70) were the most frequently isolated pathogens from milk of cows with severe mastitis. PCR was performed in 38 of 70 (54.3%) blood samples. PCR was positive in eight of 38 cases. S. uberis was found most frequently in six blood samples (8.6%). E. coli was found on PCR in one blood sample (1.4%). S. aureus was identified in one blood sample (1.4%). When Coliforms were detected in the quarter milk sample, a Limulus test was performed in the corresponding blood sample. In three of 15 cases, the Limulus test was positive (4.3% of samples). Further studies are needed to investigate the occurrence of bacteremia in cows with severe mastitis in a higher population size.

Die Anwendung des Modells „Komplexitätsstufen von aktivierenden Lernressourcen“ auf die Förderung von Informationskompetenz in deutschen Hochschulbibliotheken (2021)

Schlottke, Natalie

Das Stufenmodell „Komplexitätsstufen von aktivierenden Lernressourcen“ wurde von einem Projektteam der Fachhochschule Hannover für die Produktion von E-Learning Materialien entwickelt. Die Bachelorarbeit soll beantworten, ob das Modell in der Praxis anwendbar ist. Hierfür wird eine Analyse des Stufenmodells angestrebt. Um die Anwendbarkeit zu überprüfen, wird das Stufenmodell mit Beispielen aus wissenschaftlichen Bibliotheken abgeglichen. Die Beispiele basieren auf Lernressourcen, die aus Bibliotheken entnommen werden, die mittels E-Learning Informationskompetenz vermitteln. Für die Analyse werden die Angebote anhand der Parameter und der Lernziele des Stufenmodells kategorisiert. Um die Ergebnisse anwendbar zu machen, wird weiterhin ein Konzept für die Förderung von Informationskompetenz mit E-Learning Werkzeugen vorgeschlagen. Die Analyse des Stufenmodells zeigt auf, dass das Modell eine gute Orientierung ist, um E-Learning Ressourcen zu kategorisieren. Der Parameter Komplexität eignet sich, um die Ressourcen umfassend abzubilden, da die meisten Beispiele in das Modell einsortiert werden können. Der Schwachpunkt des Modells besteht jedoch darin, dass zu viele Parameter berücksichtigt werden, die sich gegenseitig ausschließen können. Die Ergebnisse der Analyse werden abschließend zu einem Konzept für Bibliotheken zusammengefasst. Die Theorien der Didaktik, sowie das Schwellenkonzept der Association of College & Research Libraries dienen hierbei als Grundlage. Dies zeigt auf, dass Informationskompetenz mit E-Learning Werkzeugen vermittelt werden und das Stufenmodell als Instrument dienlich sein kann.

Meta-analysis of diagnostic accuracy studies with multiple thresholds: Comparison of different approaches (2021)

Zapf, Antonia ; Albert, Christian ; Frömke, Cornelia ; Haase, Michael ; Hoyer, Annika ; Jones, Hayley E. ; Rücker, Gerta

Methods for standard meta-analysis of diagnostic test accuracy studies are well established and understood. For the more complex case in which studies report test accuracy across multiple thresholds, several approaches have recently been proposed. These are based on similar ideas, but make different assumptions. In this article, we apply four different approaches to data from a recent systematic review in the area of nephrology and compare the results. The four approaches use: a linear mixed effects model, a Bayesian multinomial random effects model, a time-to-event model and a nonparametric model, respectively. In the case study data, the accuracy of neutrophil gelatinase-associated lipocalin for the diagnosis of acute kidney injury was assessed in different scenarios, with sensitivity and specificity estimates available for three thresholds in each primary study. All approaches led to plausible and mostly similar summary results. However, we found considerable differences in results for some scenarios, for example, differences in the area under the receiver operating characteristic curve (AUC) of up to 0.13. The Bayesian approach tended to lead to the highest values of the AUC, and the nonparametric approach tended to produce the lowest values across the different scenarios. Though we recommend using these approaches, our findings motivate the need for a simulation study to explore optimal choice of method in various scenarios.

A descriptive cross-sectional study of cholera at Kakuma and Kalobeyei refugee camps, Kenya in 2018 (2020)

Kisera, Nereah ; Luxemburger, Christine ; Tornieporth, Nadia ; Otieno, George ; Inda, Javan

Introduction: cholera is a significant public health concern among displaced populations. Oral cholera vaccines are safe and can effectively be used as an adjunct to prevent cholera in settings with limited access to water and sanitation. Results from this study can inform future consideration for cholera vaccination at Kakuma and Kalobeyei. Methods: a descriptive cross-sectional study of cholera cases at Kakuma refugee camp and Kalobeyei integrated settlement was carried out between May 2017 to May 2018 (one year). Data were extracted from the medical records and line lists at the cholera treatment centres. Results: the results found 125 clinically suspected and confirmed cholera cases and one related death (CFR 0.8%). The cumulative incidence of all cases was 0.67 (95% CI=0.56-0.80) cases/1000 persons. Incidence of cholera was higher in children under the age of five 0.94(95% CI=0.63-1.36) cases/1000 persons. Children aged <5 years showed 51% increased risk of cholera compared to those aged ≥5 years (RR=1.51; 95% CI=1.00-2.31, p=0.051). Individuals from the Democratic Republic of Congo had nearly 9-fold risk of reporting cholera (RR=8.62; 95% CI=2.55-37.11, p<0.001) while individuals from South Sudan reported 7 times risk of cholera case compared to those from Somalia (RR=7.39; 95% CI=2.78-27.73, p<0.001). Conclusion: in addition to the improvement of water, sanitation and hygiene (WaSH), vaccination could be implemented as a short-medium term measure of preventing cholera outbreaks. Age, country of origin and settlement independently predicted the risk of cholera.

On-Time Delivery in Crowdshipping Systems: An Agent-Based Approach Using Streaming Data (2020)

Dötterl, Jeremias ; Bruns, Ralf ; Dunkel, Jürgen ; Ossowski, Sascha

In parcel delivery, the “last mile” from the parcel hub to the customer is costly, especially for time-sensitive delivery tasks that have to be completed within hours after arrival. Recently, crowdshipping has attracted increased attention as a new alternative to traditional delivery modes. In crowdshipping, private citizens (“the crowd”) perform short detours in their daily lives to contribute to parcel delivery in exchange for small incentives. However, achieving desirable crowd behavior is challenging as the crowd is highly dynamic and consists of autonomous, self-interested individuals. Leveraging crowdshipping for time-sensitive deliveries remains an open challenge. In this paper, we present an agent-based approach to on-time parcel delivery with crowds. Our system performs data stream processing on the couriers’ smartphone sensor data to predict delivery delays. Whenever a delay is predicted, the system attempts to forge an agreement for transferring the parcel from the current deliverer to a more promising courier nearby. Our experiments show that through accurate delay predictions and purposeful task transfers many delays can be prevented that would occur without our approach.

Towards a tractography-based risk stratification model for language area associated gliomas (2021)

Tuncer, Mehmet Salih ; Salvati, Luca Francesco ; Grittner, Ulrike ; Hardt, Juliane ; Schilling, Ralph ; Bährend, Ina ; Silva, Luca Leandro ; Fekonja, Lucius S. ; Faust, Katharina ; Vajkoczy, Peter ; Rosenstock, Tizian ; Picht, Thomas

Objectives: Injury to major white matter pathways during language-area associated glioma surgery often leads to permanent loss of neurological function. The aim was to establish standardized tractography of language pathways as a predictor of language outcome in clinical neurosurgery. Methods: We prospectively analyzed 50 surgical cases of patients with left perisylvian, diffuse gliomas. Standardized preoperative Diffusion-Tensor-Imaging (DTI)-based tractography of the 5 main language tracts (Arcuate Fasciculus [AF], Frontal Aslant Tract [FAT], Inferior Fronto-Occipital Fasciculus [IFOF], Inferior Longitudinal Fasciculus [ILF], Uncinate Fasciculus [UF]) and spatial analysis of tumor and tracts was performed. Postoperative imaging and the resulting resection map were analyzed for potential surgical injury of tracts. The language status was assessed preoperatively, postoperatively and after 3 months using the Aachen Aphasia Test and Berlin Aphasia Score. Correlation analyses, two-step cluster analysis and binary logistic regression were used to analyze associations of tractography results with language outcome after surgery. Results: In 14 out of 50 patients (28%), new aphasic symptoms were detected 3 months after surgery. The preoperative infiltration of the AF was associated with functional worsening (cc = 0.314; p = 0.019). Cluster analysis of tract injury profiles revealed two areas particularly related to aphasia: the temporo-parieto-occipital junction (TPO; temporo-parietal AF, middle IFOF, middle ILF) and the temporal stem/peri-insular white matter (middle IFOF, anterior ILF, temporal UF, temporal AF). Injury to these areas (TPO: OR: 23.04; CI: 4.11 – 129.06; temporal stem: OR: 21.96; CI: 2.93 – 164.41) was associated with a higher-risk of persisting aphasia. Conclusions: Tractography of language pathways can help to determine the individual aphasia risk profile presurgically. The TPO and temporal stem/peri-insular white matter were confirmed as functional nodes particularly sensitive to surgical injuries.

Effects of exercise training on bone mineral density and some health-related outcomes in HIV conditions : A randomized controlled trial (2020)

Ajidahun, Adedayo Tunde ; Myezwa, Hellen ; Ibeneme, Sam Chidi ; Magobotha, Sebastian ; Fortwengel, Gerhard ; Jingo, Maxwell ; Milner, Brenda ; Ravat, Sadiya ; Okoye, Ifeoma ; Schnaid, Edward ; Bischoff, Faith

Introduction: Human Immunodeficiency Virus (HIV) infection remains prevalent co-morbidity, and among fracture patients. Few studies have investigated the role of exercise interventions in preventing bone demineralization in people who have fractures and HIV. If exercise exposed, HIV-infected individuals may experience improved bone health outcomes (BMD), function, quality of life (QoL). The study will aim to assess the impact of home based exercises on bone mineral density, functional capacity, QoL, and some serological markers of health in HIV infection among Nigerians and South Africans. Methods and design: The study is an assessor-blinded randomized controlled trial. Patients managed with internal and external fixation for femoral shaft fracture at the study sites will be recruited to participate in the study. The participants will be recruited 2 weeks post-discharge at the follow-up clinic with the orthopaedic surgeon. The study population will consist of all persons with femoral fracture and HIV-positive and negative (HIV-positive medically confirmed) aged 18 to 60 years attending the above-named health facilities. For the HIV-positive participants, a documented positive HIV result, as well as a history of being followed-up at the HIV treatment and care center. A developed home based exercise programme will be implemented in the experimental group while the control group continues with the usual rehabilitation programme. The primary outcome measures will be function, gait, bone mineral density, physical activity, and QoL. Discussion: The proposed trial will compare the effect of a home-based physical exercise-training programme in the management of femoral fracture to the usual physiotherapy management programmes with specific outcomes of bone mineral density, function, and inflammatory markers.

Veränderung erzeugt Widerstand : Ein Bericht von der Mitgliederversammlung der DGSv vom 26. September 2020 in Hannover (2021)

Walpuski, Volker Jörn

Die Mitgliederversammlung der Deutschen Gesellschaft für Supervision und Coaching e. V. (DGSv) stand 2020 äußerlich im Zeichen von Covid-19 und damit Social Distancing, inhaltlich im Zeichen der konsequenten Fortführung begonnener Strategie- und Modernisierungsprozesse des Berufs- und Fachverbandes. Gleichzeitig aktualisierten diese Prozesse die Identitätsfrage des Verbandes.

Cora Baltussen in den USA : Lernerfahrungen für die Supervision in den Niederlanden und Deutschland (2021)

Walpuski, Volker Jörn

Cora Baltussen unternahm - wie zahlreiche europäische Sozialarbeitende - Anfang der 1950er Jahre eine 18-monatige Studienreise in die USA, um Casework und Supervision zu erlernen. Dieser Beitrag wertet ihren Summerreport von 1953 aus, der als Archivalie erhalten ist. So können ihre Lernerfahrungen in der historisch-kritischen Rekonstruktion kontextualisiert und in den Diskurs eingeordnet werden. Dabei werden erste Differenzierungen der frühen Supervisionsgeschichte ebenso sichtbar wie prägende Begegnungen und entstehende Netzwerke, die die Supervisionsentwicklung in Deutschland maßgeblich beeinflussten.

Scaling and Synchronization in Deterministic and Stochastic Nonlinear Dynamical Systems (2001)

Ahlers, Volker

Subject of this work is the investigation of universal scaling laws which are observed in coupled chaotic systems. Progress is made by replacing the chaotic fluctuations in the perturbation dynamics by stochastic processes. First, a continuous-time stochastic model for weakly coupled chaotic systems is introduced to study the scaling of the Lyapunov exponents with the coupling strength (coupling sensitivity of chaos). By means of the the Fokker-Planck equation scaling relations are derived, which are confirmed by results of numerical simulations. Next, the new effect of avoided crossing of Lyapunov exponents of weakly coupled disordered chaotic systems is described, which is qualitatively similar to the energy level repulsion in quantum systems. Using the scaling relations obtained for the coupling sensitivity of chaos, an asymptotic expression for the distribution function of small spacings between Lyapunov exponents is derived and compared with results of numerical simulations. Finally, the synchronization transition in strongly coupled spatially extended chaotic systems is shown to resemble a continuous phase transition, with the coupling strength and the synchronization error as control and order parameter, respectively. Using results of numerical simulations and theoretical considerations in terms of a multiplicative noise partial differential equation, the universality classes of the observed two types of transition are determined (Kardar-Parisi-Zhang equation with saturating term, directed percolation).

Der emanzipierte Patient - Eine empirische Untersuchung zum Einfluss des Arzt-Patienten-Gesprächs auf das Informationsverhalten im Web (2020)

Lein, Celina

Im Rahmen dieser Bachelorarbeit wird das Feld des Arzt-Patienten-Gesprächs und die Forschung zum digitalen Informationsverhalten verknüpft. Dabei soll empirisch überprüft werden, welche Faktoren des Gesprächs zwischen Arzt und Patient sich auf die Online-Informationssuche auswirken.

Usability Testing of Visual Policy Evaluation for Network Security Event Detection (2020)

Ahlers, Volker ; Hellmann, Bastian

The network security framework VisITMeta allows the visual evaluation and management of security event detection policies. By means of a "what-if" simulation the sensitivity of policies to specific events can be tested and adjusted. This paper presents the results of a user study for testing the usability of the approach by measuring the correct completion of given tasks as well as the user satisfaction by means of the system usability scale.

Smart Data Analytics : Schriften des Forschungsclusters Smart Data Analytics 2020 (2020)

Das Forschungscluster Smart Data Analytics stellt in dem vorliegenden Band seine Forschung aus den Jahren 2019 und 2020 vor. In der ersten Hälfte des Bandes geben 20 Kurzporträts von laufenden oder kürzlich abgeschlossenen Projekten einen Überblick über die Forschungsthemen im Cluster. Enthalten in den Kurzporträts ist eine vollständige, kommentierte Liste der wissenschaftlichen Veröffentlichungen aus den Jahren 2019 und 2020. In der zweiten Hälfte dieses Bandes geben vier längere Beiträge exemplarisch einen tieferen Einblick in die Forschung des Clusters und behandeln Themen wie Fehlererkennung in Datenbanken, Analyse und Visualisierung von Sicherheitsvorfällen in Netzwerken, Wissensmodellierung und Datenintegration in der Medizin, sowie die Frage ob ein Computerprogramm Urheber eines Kunstwerkes im Sinne des Urheberrechts sein kann.

Anwendungsorientierte Forschung für die digitale Transformation von KMU : Schriften des Forschungsclusters Industrie 4.0 (2020)

Das Forschungscluster Industrie 4.0 stellt in acht Beiträgen aktuelle Ergebnisse aus seinen vielfältigen Forschungsprojekten vor. Es werden virtuelle Techniken in der Produktentwicklung, Lehrkonzepte für Industrie 4.0, Energy Harvesting bei Antennen, Energiemanagement in Produktionsanlagen, firmenübergreifende IT-Security Anforderungen, dezentral gesteuerte Produktionsprozesse und Spracherkennung mit Mikrocontrollern behandelt.

Teleteaching – Provisorium oder langfristige Ergänzung für die Lehre? (2020)

Holtermann, Sebastian

Die vergleichende Fallstudie untersucht die Auswirkungen des Einsatzes von Videokonferenzsoftware (VKS) in einer kooperativen Lernumgebung in einem Masterseminar der Hochschule Hannover im Studiengang Unternehmensentwicklung. Es wurden 13 problemzentrierte Interviews mit Teilnehmenden eines Online- und eines Präsenzkurses geführt. Die gewonnenen Daten aus den Interviewaussagen wurden unter Anwendung des an der Hochschule eingesetzten Evaluationsfragebogens auf Plausibilität geprüft. Es wurden acht Probanden aus dem Onlinekurs und fünf Probanden aus dem vorherigen Präsenzkurs befragt. Die Interviews wurden über eine qualitative Inhaltsanalyse ausgewertet. Die zentralen Ergebnisse waren, dass das Teleteaching zwar funktioniert, die Onlinestudierenden aber eine niedrigere Aufmerksamkeit, eine gehemmte aktive Beteiligung, eine geringere Interaktion zwischen den Studierenden und eine erschwerte Interaktion in den Gruppenarbeiten wahrnehmen. Als größte Nachteile wurden die fehlenden persönlichen Kontakte und die niedrige Aufmerksamkeit identifiziert. Als größter Vorteil erwies sich die erhöhte Flexibilität durch den ersparten Anfahrtsweg. Ein für Teleteaching zentraler Erfolgsfaktor ist, dass die Kameras auch bei den Teilnehmenden angeschaltet sein sollten, damit die Aufmerksamkeit und die aktive Beteiligung gefördert werden. Zwölf der Probanden stuften den VKS-Einsatz als sinnvolle Ergänzung für Seminare ein. Präsenzseminare sind aber keinesfalls durch Onlineseminare zu ersetzen.

Korruption – Einstellung – Polizei (2020)

Heber, Frank ; Jungwirth, Simone ; Schäffer, Angelika

In diesem Beitrag werden die Ergebnisse einer Personalbefragung österreichischer Polizisten und Polizistinnen in Ausbildung geschildert, bei denen die Einstellung zu Korruption erhoben wurde. Weiterhin wurden Variablen wie Geschlecht, Alter und Bildungsgrad erhoben, die in Hellfeldforschung zu Korruption häufig als Merkmale von Korruptionstätern und Korruptionstäterinnen genannt werden. Im Fokus dieses Beitrags steht unter anderem die Frage, inwieweit sich Befunde aus dem Hellfeld von Korruption im Dunkelfeld abbilden. Zur Klärung dieser Frage werden Merkmale aus dem Hellfeld der Korruptionstäter und Korruptionstäterinnen auf eine Ursache-Wirkungs-Beziehung mit der Einstellung zu Korruption im Dunkelfeld überprüft. Zudem wird in diesem Beitrag die Frage geklärt, wie die Polizisten und Polizistinnen in Ausbildung hinsichtlich der Einstellung zu Korruption im Vergleich mit der Allgemeinbevölkerung Österreichs abschneiden. Polizisten und Polizistinnen in Ausbildung sind für das Bundesamt zur Korruptionsprävention und Korruptionsbekämpfung (kurz: BAK) die größte Zielgruppe bei der Ausbildung und Weiterbildung öffentlich Bediensteter in Österreich. Die Ergebnisse lassen erkennen, dass sich die Befunde aus dem Hellfeld von Korruption nicht im Dunkelfeld abbilden, denn die überprüften Variablen weisen insgesamt betrachtet keine substanzielle Ursache-Wirkungs-Beziehung mit der Einstellung zu Korruption auf. Hinsichtlich des Vergleichs der österreichischen Polizisten und Polizistinnen in Ausbildung mit der Allgemeinbevölkerung Österreichs zeigen sich nur geringfügige Unterschiede in der Einstellung zu Korruption. Tendenziell lehnen die Polizisten und Polizistinnen in Ausbildung Korruption eher ab als die Allgemeinbevölkerung Österreichs.

Characterization, Cure Rates and Associated Risks of Clinical Mastitis in Northern Germany (2020)

Schmenger, Anne ; Krömker, Volker

The control of clinical mastitis on dairy farms is an essential part of animal health management. Knowledge of the causative microorganisms, the cure rates achievable in the field and essential associated factors are crucial for proper control. The objectives of the present study were to characterize clinical mastitis cases in Germany and to analyze factors influencing cure rates and the recurrence rate. Milk samples of every clinical mastitis case occurring on 12 participating farms were examined cytomicrobiologically. Post-treatment quarter samples were taken after 14 and 21 days. Treatments were performed according to existing farm protocols. Of 2883 clinical mastitis cases, the most prevalent pathogens were Streptococcus (S.) uberis (20.2%) and coliforms (11.6%). In 35% of the milk samples, no bacteriological growth was detected. The overall bacteriological cure rate was 73.3%, while the cytological cure rate was 22.3%, the full cure rate 21.4% and the recurrence rate 18.8%. Regarding the pathogen distribution of severe mastitis, coliform bacteria were detected in 30.5% of the cases, whereas S. uberis was detected in 26.5% thereof. The results show that severe mastitis is caused almost as frequently by Gram-positive as by Gram-negative microorganisms. The low cytological cure rates show that the therapy needs to be further developed with regard to calming the inflammation. The obtained data can be very helpful in assessing internal mastitis scenarios and the effect of measures and therapies.

Unforced Errors bei Studien- und Abschlussarbeiten : Hinweise zur Endredaktion (2020)

Disterer, Georg

Vor der Abgabe einer Studien- oder Abschlussarbeit ist dringend eine sorgfältige Überarbeitung in Form einer Endredaktion vorzunehmen, um eine gute Bewertung der Arbeit nicht zu gefährden. Dies ist einfach; denn das Vorgehen ist schlicht und wenig aufwändig. Daher wäre es besonders ärgerlich, einfache Fehler nicht zu beheben und dafür Abzüge bei der Bewertung der Arbeit hinzunehmen. Für eine Endredaktion wird hiermit eine Anleitung vorgelegt.

Streptococcus dysgalactiae — Contagious or Environmental? (2020)

Wente, Nicole ; Krömker, Volker

Streptococcus dysgalactiae is among the most important pathogens causing bovine mastitis. Unfortunately, there is presently a lack of clear knowledge about the mode of transmission — contagious or environmental — of this pathogen. To obtain more information on this, knowledge of the genetic diversity of the isolated microorganisms at the farm level can be useful. To observe the strain variety in different herds of cattle, isolates of Strep. dysgalactiae were collected from clinical mastitis samples at different farms, and the strains were typed using the pulsed-field gel electrophoresis (PFGE) method. Overall, we performed strain typing on 93 isolates from 16 farms in Germany and used an index to describe the degree of contagiosity of Strep. dysgalactiae at each farm. This index (CI) represents the number of isolates divided by the number of strains found in mastitis milk of clinical cases within a period of 14 months. The results differed between the farms. In one farm, all six Strep. dysgalactiae cases that occurred during the study period were caused by a single strain (CI = 6), while in another farm the six cases that occurred were caused by five different strains (CI = 1.2). All other farms fell between these two extremes. This indicates that Strep. dysgalactiae infections can occur via several routes of transmission. At the farm level, strain comparisons are necessary to determine the routes of transmission. Two strains were able to survive on the farm for a minimum of 14 months.

An Immersive Multi-User Virtual Reality for Emergency Simulation Training: Usability Study (2020)

Lerner, Dieter ; Mohr, Stefan ; Schild, Jonas ; Göring, Martin ; Luiz, Thomas

Background: Virtual reality (VR) is increasingly used as simulation technology in emergency medicine education and training, in particular for training nontechnical skills. Experimental studies comparing teaching and learning in VR with traditional training media often demonstrate the equivalence or even superiority regarding particular variables of learning or training effectiveness. Objective: In the EPICSAVE (Enhanced Paramedic Vocational Training with Serious Games and Virtual Environments) project, a highly immersive room-scaled multi-user 3-dimensional VR simulation environment was developed. In this feasibility study, we wanted to gain initial insights into the training effectiveness and media use factors influencing learning and training in VR. Methods: The virtual emergency scenario was anaphylaxis grade III with shock, swelling of the upper and lower respiratory tract, as well as skin symptoms in a 5-year-old girl (virtual patient) visiting an indoor family amusement park with her grandfather (virtual agent). A cross-sectional, one-group pretest and posttest design was used to evaluate the training effectiveness and quality of the training execution. The sample included 18 active emergency physicians. Results: The 18 participants rated the VR simulation training positive in terms of training effectiveness and quality of the training execution. A strong, significant correlation (r=.53, P=.01) between experiencing presence and assessing training effectiveness was observed. Perceived limitations in usability and a relatively high extraneous cognitive load reduced this positive effect. Conclusions: The training within the virtual simulation environment was rated as an effective educational approach. Specific media use factors appear to modulate training effectiveness (ie, improvement through “experience of presence” or reduction through perceived limitations in usability). These factors should be specific targets in the further development of this VR simulation training.

Incorporating Situation Awareness into Recommender Systems (2017)

Dötterl, Jeremias ; Bruns, Ralf ; Dunkel, Jürgen

Nowadays, smartphones and sensor devices can provide a variety of information about a user’s current situation. So far, many recommender systems neglect this kind of information and thus cannot provide situationspecific recommendations. Situation-aware recommender systems adapt to changes in the user’s environment and therefore are able to offer recommendations that are more appropriate for the current situation. In this paper, we present a software architecture that enables situation awareness for arbitrary recommendation techniques. The proposed system considers both (semi-)static user profiles and volatile situational knowledge to obtain meaningful recommendations. Furthermore, the implementation of the architecture in a museum of natural history is presented, which uses Complex Event Processing to achieve situation awareness.

Der Erfolgsfaktor Bürgerkommunikation im Kontext der Projektkommunikation von Bauvorhaben : Handlungsempfehlungen für die Immobilien-PR (2020)

Ritter, Stella

Die Gesellschaft ist geprägt von einem zunehmenden Bedürfnis nach Mitbestimmung und damit auch Beteiligung. In Zeiten mangelnder Wohnangebote ist das Interesse besonders groß, wenn bedeutsame Baumaßnahmen thematisiert werden und große Veränderungen mit sich bringen. Die positive Resonanz auf innerstädtische Immobilienprojekte ist alles andere als selbstverständlich, dabei liegen die Interessen häufig eng beieinander. "Man wird natürlich nie alle zufriedenstellen können" aber häufig mangelt es an ausreichender Kommunikation und Aufklärungsarbeit. Die Wissenschaftsarbeit beschäftigt sich mit der Frage, welche Ansprüche an Bürgerkommunikation bestehen und welche Chancen sich daraus für die Kommunikation von Bauprojekten ergeben. Daraus resultiert ein Lösungsansatz für die Immobilien-Public-Relations (PR).

Arbeitsklima in der Wirtschaftsinformatik spürbar verschieden (2020)

Disterer, Georg

Untersuchungen zu Berufen der Wirtschaftsinformatik bleiben weiterhin interessant, wenn sie helfen können, dem mittlerweile länger anhaltenden IT-Fachkräftemangel entgegenzuwirken. Eine Untersuchung der Hochschule Hannover zu Wirtschaftsinformatikern/-informatikerinnen in den ersten zehn Jahren im Beruf zeigt deren berufliche Ziele und die berufliche Zufriedenheit, die sie erlangen. Deutlich wird, dass Frauen und Männer das Arbeitsklima und die Arbeitsbedingungen sehr unterschiedlich wahrnehmen und daher auch unterschiedlich zufrieden sind. Dabei bemängeln Frauen vor allem Merkmale, die mit „fehlender Fairness“ zu beschreiben sind.

Potenziale von PROFIenergy in der Prozessindustrie (2020)

Niemann, Karl-Heinz ; Andreas, Würger

Der vorliegende Beitrag beschreibt Einsatzpotenziale des Energiemanagementprofils PROFIenergy in der Prozessindustrie. Der Blick auf den Status von Energieeffizienzmaßnahmen in der Prozessindustrie zeigt, dass diese im Wesentlichen innerhalb der verfahrenstechnischen Optimierung angesiedelt sind. Noch hat sich der durchgängige Einsatz von technischen Energiemanagementsystemen (tEnMS) nicht etabliert. Diese Arbeit fokussiert Vorteile des tEnMS-Einsatzes und präsentiert „Best Practice“- Beispiele in der Prozessindustrie. Abschließend wird aufgezeigt, welches Potenzial das Energiemanagementprofil PROFIenergy liefern kann und welche Anwendungsfälle sich damit abdecken lassen.

Personalentwicklung Online - The Big Fives (2020)

Seibold, Sven ; Linssen, Ruth ; Flügel, Steffen ; Noor, Jonathan

Am Beispiel des Fünf-Faktoren-Modells der Persönlichkeit aus der Psychologie (Big 5) wird exemplarisch gezeigt, wie komplexe Lerninhalte adäquat für eine Onlinevermittlung aufbereitet werden können und wie man zugleich die Lernmotivation der Teilnehmenden erhöhen kann. Hierfür wurde eine bestehende Lerneinheit mit Präsenzvermittlung im Umfang von einem halben Tag in ein Onlineformat übertragen. Der Kern des Onlineformats beinhaltet sechs Lernvideos, bestehend aus einem Videofilm zum Modellüberblick und je einem Videofilm für jeden der fünf Faktoren des Modells. In den Videofilmen agieren die fünf Mitglieder einer Rockband sowie ein Erzähler aus dem Off. Jedes Bandmitglied steht prototypisch für einen der fünf Faktoren des Modells. Die Darstellung der fünf Bandmitglieder (The Big Fives) und deren Interaktion werden als Grundlage genutzt, um die Anwendung des Fünf-Faktoren-Modells zu üben.

Return to work after ischemic stroke in young adults : A registry-based follow-up study (2018)

Aarnio, Karoliina ; Rodríguez-Pardo, Jorge ; Siegerink, Bob ; Hardt, Juliane ; Broman, Jenna ; Tulkki, Lauri ; Haapaniemi, Elena ; Kaste, Markku ; Tatlisumak, Turgut ; Putaala, Jukka

Objective We aimed to investigate the proportion of young patients not returning to work (NRTW) at 1 year after ischemic stroke (IS) and during follow-up, and clinical factors associated with NRTW. Methods Patients from the Helsinki Young Stroke Registry with an IS occurring in the years 1994–2007, who were at paid employment within 1 year before IS, and with NIH Stroke Scale score ≤15 points at hospital discharge, were included. Data on periods of payment came from the Finnish Centre for Pensions, and death data from Statistics Finland. Multivariate logistic regression analyses assessed factors associated with NRTW 1 year after IS, and lasagna plots visualized the proportion of patients returning to work over time. Results We included a total of 769 patients, of whom 289 (37.6%) were not working at 1 year, 323 (42.0%) at 2 years, and 361 (46.9%) at 5 years from IS. When adjusted for age, sex, socioeconomic status, and NIH Stroke Scale score at admission, factors associated with NRTW at 1 year after IS were large anterior strokes, strokes caused by large artery atherosclerosis, high-risk sources of cardioembolism, and rare causes other than dissection compared with undetermined cause, moderate to severe aphasia vs no aphasia, mild and moderate to severe limb paresis vs no paresis, and moderate to severe visual field deficit vs no deficit. Conclusions NRTW is a frequent adverse outcome after IS in young adults with mild to moderate IS. Clinical variables available during acute hospitalization may allow prediction of NRTW.

Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3 (2019)

Kühnisch, Jirko ; Herbst, Christopher ; Al-Wakeel-Marquard, Nadya ; Dartsch, Josephine ; Holtgrewe, Manuel ; Baban, Anwar ; Mearini, Giulia ; Hardt, Juliane ; Kolokotronis, Konstantinos ; Gerull, Brenda ; Carrier, Lucie ; Beule, Dieter ; Schubert, Stephan ; Messroghli, Daniel ; Degener, Franziska ; Berger, Felix ; Klaassen, Sabine

The underlying genetic mechanisms and early pathological events of children with primary cardiomyopathy (CMP) are insufficiently characterized. In this study, we aimed to characterize the mutational spectrum of primary CMP in a large cohort of patients ≤18 years referred to a tertiary center. Eighty unrelated index patients with pediatric primary CMP underwent genetic testing with a panel-based next-generation sequencing approach of 89 genes. At least one pathogenic or probably pathogenic variant was identified in 30/80 (38%) index patients. In all CMP subgroups, patients carried most frequently variants of interest in sarcomere genes suggesting them as a major contributor in pediatric primary CMP. In MYH7, MYBPC3, and TNNI3, we identified 18 pathogenic/probably pathogenic variants (MYH7 n = 7, MYBPC3 n = 6, TNNI3 n = 5, including one homozygous (TNNI3 c.24+2T>A) truncating variant. Protein and transcript level analysis on heart biopsies from individuals with homozygous mutation of TNNI3 revealed that the TNNI3 protein is absent and associated with upregulation of the fetal isoform TNNI1. The present study further supports the clinical importance of sarcomeric mutation-not only in adult-but also in pediatric primary CMP. TNNI3 is the third most important disease gene in this cohort and complete loss of TNNI3 leads to severe pediatric CMP.

Correction to: Healthcare professionals’ perspectives on working conditions, leadership, and safety climate: a crosssectional study (2020)

Wagner, Anke ; Rieger, Monika A. ; Manser, Tanja ; Sturm, Heidrun ; Hardt, Juliane ; Martus, Peter ; Lessing, Constanze ; Hammer, Antje

Correction to: https://doi.org/10.1186/s12913-018-3862-7 In the original publication of this article, the authors missed that reverse coding was necessary for the item “Do you work separate from your colleagues?” before calculating the scale ‘social relations’. So they corrected the analysis accordingly. The results with the revised scale show that there are no longer any significant differences between nurses and physicians with regard to this scale.

Healthcare professionals’ perspectives on working conditions, leadership, and safety climate: a cross-sectional study (2019)

Wagner, Anke ; Rieger, Monika A. ; Manser, Tanja ; Sturm, Heidrun ; Hardt, Juliane ; Martus, Peter ; Lessing, Constanze ; Hammer, Antje

Background: Promoting patient and occupational safety are two key challenges for hospitals. When aiming to improve these two outcomes synergistically, psychosocial working conditions, leadership by hospital management and supervisors, and perceptions of patient and occupational safety climate have to be considered. Recent studies have shown that these key topics are interrelated and form a critical foundation for promoting patient and occupational safety in hospitals. So far, these topics have mainly been studied independently from each other. The present study investigated hospital staffs’ perceptions of four different topics: (1) psychosocial working conditions, (2) leadership, (3) patient safety climate, and (4) occupational safety climate. We present results from a survey in two German university hospitals aiming to detect differences between nurses and physicians. Methods: We performed a cross-sectional study using a standardized paper-based questionnaire. The survey was conducted with nurses and physicians to assess the four topics. The instruments mainly consisted of scales of the German version of the COPSOQ (Copenhagen Psychosocial Questionnaire), one scale of the Copenhagen Burnout Inventory (CBI), scales to assess leadership and transformational leadership, scales to assess patient safety climate using the Hospital Survey on Patient Safety Culture (HSPSC), and analogous items to assess occupational safety climate. Results: A total of 995 completed questionnaires out of 2512 distributed questionnaires were returned anonymously. The overall response rate was 39.6%. The sample consisted of 381 physicians and 567 nurses. We found various differences with regard to the four topics. In most of the COPSOQ and the HSPSC-scales, physicians rated psychosocial working conditions and patient safety climate more positively than nurses. With regard to occupational safety, nurses indicated higher occupational risks than physicians. Conclusions: The WorkSafeMed study combined the assessment of the four topics psychosocial working conditions, leadership, patient safety climate, and occupational safety climate in hospitals. Looking at the four topics provides an overview of where improvements in hospitals may be needed for nurses and physicians. Based on these results, improvements in working conditions, patient safety climate, and occupational safety climate are required for health care professionals in German university hospitals – especially for nurses.

Guidelines and recommendations for ensuring Good Epidemiological Practice (GEP): a guideline developed by the German Society for Epidemiology (2019)

Hoffmann, Wolfgang ; Latza, Ute ; Baumeister, Sebastian E. ; Brünger, Martin ; Buttmann-Schweiger, Nina ; Hardt, Juliane ; Hoffmann, Verena ; Karch, André ; Richter, Adrian ; Schmidt, Carsten Oliver ; Schmidtmann, Irene ; Swart, Enno ; van den Berg, Neeltje

Objective To revise the German guidelines and recommendations for ensuring Good Epidemiological Practice (GEP) that were developed in 1999 by the German Society for Epidemiology (DGEpi), evaluated and revised in 2004, supplemented in 2008, and updated in 2014. Methods The executive board of the DGEpi tasked the third revision of the GEP. The revision was arrived as a result of a consensus-building process by a working group of the DGEpi in collaboration with other working groups of the DGEpi and with the German Association for Medical Informatics, Biometry and Epidemiology, the German Society of Social Medicine and Prevention (DGSMP), the German Region of the International Biometric Society (IBS-DR), the German Technology, Methods and Infrastructure for Networked Medical Research (TMF), and the German Network for Health Services Research (DNVF). The GEP also refers to related German Good Practice documents (e.g. Health Reporting, Cartographical Practice in the Healthcare System, Secondary Data Analysis). Results The working group modified the 11 guidelines (after revision: 1 ethics, 2 research question, 3 study protocol and manual of operations, 4 data protection, 5 sample banks, 6 quality assurance, 7 data storage and documentation, 8 analysis of epidemiological data, 9 contractual framework, 10 interpretation and scientific publication, 11 communication and public health) and modified and supplemented the related recommendations. All participating scientific professional associations adopted the revised GEP. Conclusions The revised GEP are addressed to everyone involved in the planning, preparation, execution, analysis, and evaluation of epidemiological research, as well as research institutes and funding bodies.

Vergleichsanalyse des Therapieerfolgs bei HIV-Infizierten (2019)

Kaczmarek-Sondej, Wiktoria

Die Anzahl an mit dem HI-Virus Neuinfizierten sinkt aufgrund der stetig voranschreitenden Forschung im Bereich der Therapie der HIV-Infektion kontinuierlich. Durch die erforschten HIV-Medikamente, wie zum Beispiel Biktarvy®, Atripla®, Eviplera® oder Genvoya® kann bei nicht vorliegenden Resistenzen oftmals ein bemerkenswerter Therapieerfolg erzielt werden. Doch der Therapieerfolg wird von vielen verschiedenen Faktoren beeinflusst. Um dies genauer zu analysieren, handelt die vorliegende Bachelorarbeit von der Untersuchung des Einflusses verschiedener Parameter auf den Therapieerfolg von HIV-Infizierten. Da es zahlreiche Einflussfaktoren gibt, wurde eine engere Auswahl getroffen. In dieser Arbeit wurde daher der Einfluss von dem Geschlecht, der Therapiekombination, der Altersgruppe, den vergangenen Jahren seit der gestellten Diagnose sowie der Dauer der bereits eingenommenen Therapie auf die Laborwerte „Viruslast“ und „CD4-Zellzahl“ untersucht. Ziel der Bachelorarbeit war es, mehr Daten zu gewinnen, die Ergebnisse des Einflusses der soeben genannten Kenngrößen enthalten. Für die statistische Vergleichsanalyse wurden Daten aus der seit knapp 20 Jahren bestehenden HIV-Datenbank der Medizinischen Hochschule Hannover, Abteilung Rheumatologie und Immunologie, herangezogen. Um die Ergebnisse dieser Bachelorarbeit zusammenzufassen, lässt sich resümieren, dass bei mehr als der Hälfte der Patienten, genauer gesagt bei 51 anhand der Viruslast und 57 von je 72 Patienten anhand der CD4-Zellen, ein Therapieerfolg erzielt werden konnte. Vor allem bei den Einflussgrößen Geschlecht und Therapiekombination konnte ein bemerkenswerter Einfluss auf den Therapieerfolg festgestellt werden. Bei den weiteren Parametern Altersgruppe, Diagnosedauer und Therapiedauer ist kein statistisch signifikanter Unterschied ermittelt worden.

End-of-Life Options for Bio-Based Plastics in a Circular Economy—Status Quo and Potential from a Life Cycle Assessment Perspective (2020)

Spierling, Sebastian ; Venkatachalam, Venkateshwaran ; Mudersbach, Marina ; Becker, Nico ; Herrmann, Christoph ; Endres, Hans-Josef

The bio-based plastic market is forecast to grow in the next years. With a growing market share and product range, the implementation of circular thinking is becoming more and more important also for bio-based plastics to enable a sound circular economy for these group of plastics. Therefore, it is important to assess the environmental performance for different end-of-life options of bio-based plastics from an early stage on. This review presents a comprehensive overview on the current status quo of different end-of-life options for bio-based plastics from an environmental perspective. Based on the status quo and the corresponding impact assessment results, the global plastic demand as well as the technical substitution potential of bio-based plastics, the environmental saving potential in case of the different end-of-life options was calculated. The review shows that there is a focus on polylactic acid (PLA) regarding end-of-life assessment, with studies covering all end-of-life options. The focus of the impact assessment has been set on global warming potential (GWP). With respect to GWP, the analysis of a future global potential of PLA showed, for mechanical recycling, the highest saving potential with 94.1 Mio. t CO2-eq. per year in comparison to virgin material.

Crowd-basierte Luftqualitätsmessungen mit der Complex Event Processing Engine Siddhi auf Raspberry Pi (2020)

Engelhardt, Andreas

Unter Crowdsensing versteht man Anwendungen, in denen Sensordaten kollaborativ von einer Menge von Freiwilligen erhoben werden. So kann Crowdsensing eingesetzt werden um die Luftqualität an Orten zu messen, an denen keine fest installierten Sensoren verfügbar sind. In Crowdsensing-Systemen müssen die Teilnehmer koordiniert und die Messdaten verarbeitet werden, um relevante Daten zu erhalten. Im Rahmen der Abschlussarbeit wurde ein System konzipiert und prototypisch umgesetzt, das auf einem Raspberry Pi (unter Einsatz geeigneter Sensoren) Sensordaten erhebt und mit der Complex Event Processing Technologie verarbeitet.

Selbst- und Zeitmanagement : Workbook (2020)

Wesely, Sabine

Wie kann man den empfundenen Alltagsstress bewältigen und eigene, sinnvolle Ziele erreichen? Woher kommt die Zeitnot und was kann man tun? Gibt es Faktoren, die Glück und Erfolg fördern? Was kann man in seinem Studien- und Arbeitsalltag tun, um sich wohl zu fühlen und erfolgreich zu sein? Welche Zeitmanagement-Tools helfen bei der Organisation von Studium und Arbeitsalltag? Diese und weitere Fragen werden im Workbook beantwortet. Der Selbstmanagement-Prozesskreis wird vorgestellt, verschiedene Modelle, Prinzipien und Techniken werden vermittelt. Mit vielen Reflexionsfragen und Übungen.

Bacterial Load of the Teat Apex Skin and Associated Factors at Herd Level (2020)

Hohmann, Maria-Franziska ; Wente, Nicole ; Zhang, Yanchao ; Krömker, Volker

In order to reduce antimicrobial treatment and prevent environmental mastitis, the aim of the present study was to investigate associations between herd level factors and microbial load on teat ends with environmental mastitis pathogens. Quarterly farm visits of 31 dairy farms over a one-year period were used for statistical analysis. During each farm visit, teat-skin swabs, bedding and air samples were taken and management practices and herd parameters were documented. Total mesophilic bacteria, esculin-positive streptococci and coliform bacteria were examined in the laboratory procedures from teat skin and environmental samples. Esculin-positive streptococci and coliform bacteria on teat ends increased with high temperature–humidity indices (THI) in the barn during the spring and summer. Significantly more coliform bacteria on teat ends were found in herds with an increased percentage of normal or slightly rough teat ends. Cleaning cubicles more frequently, pre-cleaning teats before milking as well as post-dipping them after milking had a decreasing effect of teat-skin load with total mesophilic and coliform bacteria at the herd level. To conclude, teat-skin bacterial load with environmental pathogens is subject to fluctuations and can be influenced by aspects of farm hygiene.

Automatisierte Kundenkommunikation: Bot or Not? Eine Untersuchung der Akzeptanz von textbasierten Dialogsystemen in der Kundenkommunikation von Unternehmen (2020)

Nagahi, Sweety

Die Nutzung von Messenger-Diensten hat die Nutzung von sozialen Medien übertroffen. Diese Mediennutzung bringt veränderte Erwartungen an Unternehmen mit sich. Unternehmen begegnen den Erwartungen ihrer Kund*innen in der Online-Kundenkommunikation mit dem Einsatz textbasierter Dialogsysteme. Im Facebook-Messenger wurden 2018 bereits über 300.000 Chatbots angeboten. Das Problem ist, dass Studien seit mehreren Jahren aufzeigen, dass diese Kommunikationstechnologie sich bei den Kund*innen noch nicht durchgesetzt hat und häufig noch skeptisch betrachtet wird. Für Unternehmen ist es daher notwendig zu verstehen, welche Kriterien erfüllt sein müssen, um die Akzeptanzbildung der Kund*innen gegenüber textbasierten Dialogsystemen positiv zu beeinflussen. Das Ziel dieser Arbeit ist es zu betrachten, inwiefern die Eigenschaften textbasierter Dialogsysteme die Akzeptanzkriterien der Kund*innen erfüllen können. Dazu wird die folgende Forschungsfrage gestellt: Wie akzeptieren Kunden den Einsatz textbasierter Dialogsysteme in der Online-Kundenkommunikation von Unternehmen? Um die Forschungsfrage zu beantworten, wird eine Literaturanalyse durchgeführt. Die Literatur wird mit Studienergebnissen verglichen, um Übereinstimmungen und Abweichungen herauszuarbeiten. Eine Akzeptanzanalyse hat ergeben, dass Kund*innen textbasierte Dialogsysteme vor allem akzeptieren, wenn sie darin einen Nutzen erkennen. Jedoch beeinflussen neben nutzenorientierten Faktoren auch emotionale Faktoren die Akzeptanz. Auf dieser Grundlage ist es empfehlenswert, positive und negative Einflussfaktoren des Akzeptanzprozesses zu identifizieren und die Gestaltung textbasierter Dialogsysteme an die Kund*innen anzupassen, bevor diese eingesetzt werden.

Musterlösungen in Graja als Mechanismus für Regressionstests (2020)

Herschel, Marc

Der Autobewerter Graja, der in der Lehre zum Bewerten studentischer Java-Programme verwendet wird, stellt ein komplexes Softwaresystem dar. Aufgrund einer kaum vorhandenen Testabdeckung durch Modul- und Integrationstests, ist die Gewährleistung der fehlerfreien Funktionalität in Hinsicht auf die Weiterentwicklung nicht garantiert. Da sich Graja auf das ProFormA-Aufgabenformat stützt, stellt sich die Frage, inwiefern sich die im ProFormA-Aufgabenformat vorausgesetzten Musterlösungen, für einen automatisierten Regressionstestmechanismus eignen. Das Ziel dieser Forschung ist es ein Konzept, für einen solchen Regressionstestmechanismus zu erstellen und mithilfe einer Referenzimplementierung als Graja-Erweiterung in die Praxis umzusetzen. Der daraus entstandene Mechanismus operiert durch Verhaltensaufzeichnung und Verhaltensabgleich und konvertiert so das in Graja beobachtete Bewertungsverhalten einer Musterlösung in einen Testfall. In der Testphase findet anschließend ein Abgleich des Soll-Verhaltens eines Testfalls und des beobachteten Ist-Verhaltens einer Musterlösung statt. Die Differenzen dieses Abgleichs sind als potenzielle Regressionen zu behandeln, da diese eine semantische Änderung des Bewertungsergebnisses darstellen. Um diesen Verhaltensabgleich robust und mit möglichst wenigen Fehlalarme zu realisieren, wurden die in Graja verwendeten Datenmodelle auf Eignung bezüglich einer Verhaltensaufzeichnung untersucht. Außerdem fand eine Datenaufzeichnung mit einer Teilmenge der Musterlösungen statt. Nachfolgend wurde eine Analyse dieser Rohdaten, mit dem Ziel potenzielles Rauschen innerhalb der Aufzeichnungen zu detektieren, durchgeführt. So konnte letztendlich eine Strategie für eine Rauschunterdrückung innerhalb der Verhaltensaufzeichnung entwickelt werden. Abschließend wurde ein Datenmodell entwickelt, das erlaubt, die durch den Verhaltensabgleich detektierten Regressionen verständlich und lokalisierbar darzustellen. Der durch diese Arbeit entstandene automatisierte Regressionstestmechanismus stellt somit eine Grundlage für die Gewährleistung der korrekten Bewertungsfunktionalität innerhalb des Graja-Entwicklungsprozesses dar. Durch das Detektieren von Regressionen mithilfe der Musterlösungen, lassen sich nun Änderungen an Graja gewissenhaft in eine Produktionsumgebung übernehmen.

Realisierbarkeit der webseitenübergreifenden Nutzerverfolgung ohne die Verwendung von Cookies in der Europäischen Union (2020)

Griese, Valentin

Die Nutzerverfolgung im Internet durch die Verwendung von Browsercookies ist gängige Praxis, doch haben diverse datenschutzrechtliche Entwicklungen der letzten Jahre zugunsten der Verbraucher diese Form des Trackings in vielerlei Hinsicht eingeschränkt und auch die Usability von Websites maßgeblich beeinträchtigt. Um weiterhin eine Personalisierung von Werbung und anderen Inhalten unter Wahrung der Nutzbarkeit und Rechte der Nutzer zu gewährleisten, ist es unausweichlich, eine neue Methode zur Identifizierung von Besuchern zu etablieren. Das Ziel dieser Arbeit ist, verschiedene Trackingtechnologien unter Berücksichtigung gegebener Rahmenbedingungen im Rechtsraum der Europäischen Union in ihrer Funktionsweise zu vergleichen und die nach derzeitigem Stand realistische Nachfolgetechnologie zum Tracking via Cookies zu benennen – Fingerprinting. Dieses überzeugt in Bezug auf seine Langlebigkeit und rechtliche Vereinbarkeit, den Implementierungsaufwand sowie den Umfang der sammelbaren Daten. Darauf aufbauend ist eine statistische Untersuchung zur Verbreitung von Methoden aus dem Feld des Fingerprintings auf den meistgenutzten Internetseiten durchgeführt worden. Dabei ergibt sich, dass Informationen, die zur Erstellung eines Fingerprints genutzt werden können, von fast allen Websites abgefragt werden, jedoch durchschnittlich nur wenige verschiedene Arten von Fingerprints genutzt werden. Auf einigen Websites werden durch größere dritte Unternehmen Fingerprints erfasst, der Opt-in-Status hingegen hat in den meisten Fällen für die Praktizierung von Fingerprinting keine Relevanz. Da Fingerprinting auch für schädliche Zwecke, zum Beispiel das Verteilen von potenterer Schadsoftware, verwendet werden kann, ist die Reaktion von Browserentwicklern und -nutzern auf die Entwicklung von derzeitigen und zukünftigen Fingerprintingkonzepten ungewiss, und auch die rechtliche Lage der nächste Jahre hängt von angekündigten Verordnungen ab, die in ihrem Inhalt noch nicht bekannt sind.

Content-Strategien im Luxusmodemarketing (2020)

Weichselgartner, Sarah

Die Bachelorarbeit "Content-Strategien im Luxusmodemarketing" befasst sich mit den jeweiligen Besonderheiten von Content-Strategie und Luxusmodemarketing. Diese Ansatzpunkte werden zur Hilfe genommen, um die jeweiligen Disziplinen aufeinander zu beziehen. Dabei spielen bei der Content-Strategie die Faktoren Zielgruppe, Zeitpunkt, Inhalt, Kanäle und Formate eine übergeordnete Rolle, während im Luxusmodemarketing die Symbolkraft der Marke, die Saisonalität der Mode, die Visualität sowie die Akzeptanz seitens des Konsumenten von Bedeutung sind. Mithilfe dieser Kernaspekte, die in dieser Arbeit anhand von Theorien und Modellen untersucht werden, können Bezugspunkte zu den beiden Disziplinen hergestellt werden. Der Theorieteil erläutert diese Facetten und arbeitet heraus, welche genauen Muster innerhalb der Content-Strategie sowie des Luxusmodemarketings vorliegen. Schließlich beschreibt der Anwendungsteil, wie die relevanten Zielgruppen, die passenden Inhalte, der richtige Zeitpunkt, die erforderlichen Kanäle und die angemessenen Formate auszusehen haben, um eine Content-Strategie erfolgreich im Luxusmodemarketing zu implementieren. Diese Arbeit versucht dies anhand der gewonnenen theoretischen Erkenntnisse sowie entsprechenden Praxisbeispielen näher zu betrachten.

Verwendung von Subroutinen in der genetischen Programmierung zur Lösung allgemeiner Problemstellungen (2020)

Drangmeister, Robin

Insbesondere aufgrund der Zugehörigkeit zum sehr aktuellen und viel betrachteten Thema Machine Learning ist die genetische Programmierung mit ihren vielseitigen Anwendungsmöglichkeiten ein sehr interessantes Gebiet. Wie in allen Forschungsschwerpunkten gibt es auch hier viele Ansätze die standardmäßige Vorgehensweise weiter zu verbessern – einer dieser Ansätze ist die Verwendung von Subroutinen. Diese könnten in diesem Kontext auch als Methoden, Funktionen oder ähnliches bezeichnet werden und bedeuten, dass vom Algorithmus neben dem eigentlichen Programm auch wiederverwendbare Folgen von Anweisungen entwickelt werden, die über einen Bezeichner an beliebigen Stellen verwendet werden können. Hierfür gibt es bereits diverse Konzepte, die in Tests sehr gute Ergebnisse erzielt haben und eine Verbesserung gegenüber der standardmäßigen genetischen Programmierung ohne Subroutinen erreichen konnten. Diese Tests fanden allerdings immer in sehr spezialisierten Testumgebungen statt. Besonders interessant sind allerdings solche Systeme zur genetischen Programmierung, die (theoretisch) beliebige Probleme lösen kann, da sie für eine Vielzahl von Problemstellungen verwendet werden können. Das Ziel dieser Arbeit ist es, zu untersuchen, ob und inwiefern die Verwendung von Subroutinen auch in einem solchen allgemeinen System zur genetischen Programmierung, das theoretisch dazu in der Lage ist, beliebige Probleme zu lösen, möglich und sinnvoll ist.

Review of Literature To Understand Role of Pharmacy Professional in Health Management (2020)

Limaye, Dnyanesh

Background: The mission of the pharmacy profession is to improve public health through ensuring safe, effective, and appropriate use of medications. Population health management (PHP) is a process wherein opportunities are identified to improve the quality of health care delivered and thereby, promote better health outcomes for patients. Rationale: As concept of PHP is extremely important in today’s context, it is helpful to integrate data related to pharmacist in population health management practices. Authors conducted a systematic review of the literature on role of pharmacist in population health management practices. Method: We conducted a systematic review of the literature on literature on role of pharmacist in population health management practices by searching, PubMed Medline database using the following combination of keywords – pharmacist, population health. Truncation was used to ensure retrieval of all possible variations of search terms. The search was limited to articles published between 1st January 2015 and 31st December 2019, human studies and English language. Results: Initial search resulted in a total of 281 studies, title abstract review to remove irrelevant studies resulted in 256 studies. Yearly trend showed that number of publications are decreasing. Highest number of publications were from Europe (47; 18%) and 29 publications (11%) discussed role of pharmacist in population health management of subjects in the age group of 10 to 20 years. Twenty five publications mentioned health management was done in the community settings. Advice on the lifestyle was mentioned in 242 (96%) and 10 (4%) publications offered advice about drugs during the health management. Pharmacists played important roles in population health management for e.g. as care provider in exploring the challenges faced in clinics for management of Type 2 DM. Pharmacists played an important role in increasing the quality of life of patients. Discussion: Population health management concept has evolved steadily over the past few decades and is now contributing to the ‘patient care journey’ at all stages. There were 24 (9%) publications from India. Specially designed and implemented Pharm D program would play a major role in Indian health care system in future. This will give an opportunity to pharmacists to work more prominently in Indian health care system. Conclusion: Authors are of the opinion that this is the first review encompassing the topic of pharmacist and population health management in the global context. It is clear that there is a global trend of moving towards involvement of pharmacist in healthcare management. This enables pharmacists to assume an expanded role and at same time it necessitates reforms in pharmacy education and practice

Digitalisierte Beratung zur effizienteren Selbstoptimierung : Kritische Anmerkungen zu digitalen Formaten arbeitsbezogener Beratung aus einer Gouvernementalitätsperspektive (2020)

Walpuski, Volker Jörn

»Digital(isiert)e« Beratung verspricht neben Innovation auch Flexibilität, Ubiquität, Globalität, Geschwindigkeit und Legitimität durch evidenzbasierte Wirksamkeit. Für eine sozialwissenschaftlich fundierte arbeitsweltliche Beratung wie Coaching und Supervision ist danach zu fragen, welches Menschen- und Weltbild sich hinter der Digitalisierung verbirgt und welche Anliegen sie transportiert. Dazu wird mit den Theorien Michel Foucaults der gegenwärtige Diskurs auf Steuerungslogiken und Machtverhältnisse hin kritisch analysiert. Dabei zeigt sich, dass die Digitalisierung das »Zeitalter der Gouvernementalität« (Foucault) festigt: Humanistisch geprägte Werte und Ziele wie Reflexion, Anerkennung und Selbsterkenntnis treten in den Hintergrund, während die Nutzbarmachung und Optimierung des Selbst sowie des Beratungsprozesses wichtiger werden: Beratung will und muss effizienzgetrieben ihre Wirksamkeit evidenzbasiert legitimieren, und Digitalisierung erleichtert dies.

Nutzerzufriedenheit mit der Bibliothek der Hochschule Hannover: Eine empirische Untersuchung (2020)

Poets, Rebecca

Durch den Wandel des bibliothekarischen Selbstverständnisses zum zunehmend wirtschaftlich geführten Dienstleistungsbetrieb gewinnt die Nutzerorientierung im Bibliothekssektor an Bedeutung. Insbesondere Nutzerzufriedenheit ist in diesem Kontext ein wichtiges Ziel von zukunftsorientierten Bibliotheken. Für die Bibliothek der Hochschule Hannover ist aus diesem Grund im Mai 2020 eine empirische Zufriedenheitsstudie unter den Mitgliedern der Hochschule durchgeführt worden. Es wurden Nutzungseigenschaften sowie Ansichten bezüglich Dienstleistungen, Lokalitäten und Gesamteindrücken erhoben. Ergänzend zur Auswertung dieser Ergebnisse wird in dieser Arbeit ein Vergleich mit denen der bis dato jüngsten Zufriedenheitsstudie von 2009 gezogen. Ziel der onlinebasierten Befragung sowie des Vergleichs ist die Ermittlung von Nutzerbedürfnissen und Kritikpunkten, um eine fundierte Entwicklungsempfehlung für die Bibliothek erstellen zu können. Maßnahmen, die auf dieser Empfehlung basieren, sollen eine Steigerung der Nutzerzufriedenheit ermöglichen. Die Analyse der Antworten lässt vor allem auf einen Mangel des selbstständigen Informierens über die Angebote der Bibliothek sowie deren Nutzung für das wissenschaftliche Arbeiten schließen. Daher werden insbesondere eine Verbesserung der aktiven Kommunikation mit den Zielgruppen und die Förderung der Informationskompetenz der Nutzer empfohlen.

Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study (2020)

Conti, Alfredo ; Acker, Gueliz ; Pontoriero, Antonio ; Hardt, Juliane ; Kluge, Anne ; Cacciola, Alberto ; Iatì, Giuseppe ; Kufeld, Markus ; Budach, Volker ; Vajkoczy, Peter ; Beltramo, Giancarlo ; Pergolizzi, Stefano ; Bergantin, Achille ; Loebel, Franziska ; Parisi, Silvana ; Senger, Carolin ; Romanelli, Pantaleo

Background: Stereotactic radiosurgery (SRS) is an effective treatment for trigeminal neuralgia (TN). Nevertheless, a proportion of patients will experience recurrence and treatment-related sensory disturbances. In order to evaluate the predictors of efficacy and safety of image-guided non-isocentric radiosurgery, we analyzed the impact of trigeminal nerve volume and the nerve dose/volume relationship, together with relevant clinical characteristics. Methods: Two-hundred and ninety-six procedures were performed on 262 patients at three centers. In 17 patients the TN was secondary to multiple sclerosis (MS). Trigeminal pain and sensory disturbances were classified according to the Barrow Neurological Institute (BNI) scale. Pain-free-intervals were investigated using Kaplan Meier analyses. Univariate and multivariate Cox regression analyses were performed to identify predictors. Results: The median follow-up period was 38 months, median maximal dose 72.4 Gy, median target nerve volume 25mm3, and median prescription dose 60 Gy. Pain control rate (BNI I-III) at 6, 12, 24, 36, 48, and 60 months were 96.8, 90.9, 84.2, 81.4, 74.2, and 71.2%, respectively. Overall, 18% of patients developed sensory disturbances. Patients with volume ≥ 30mm3 were more likely to maintain pain relief (p = 0.031), and low integral dose (< 1.4 mJ) tended to be associated with more pain recurrence than intermediate (1.4–2.7 mJ) or high integral dose (> 2.7 mJ; low vs. intermediate: log-rank test, χ2 = 5.02, p = 0.019; low vs. high: log-rank test, χ2 = 6.026, p = 0.014). MS, integral dose, and mean dose were the factors associated with pain recurrence, while re-irradiation and MS were predictors for sensory disturbance in the multivariate analysis. Conclusions: The dose to nerve volume ratio is predictive of pain recurrence in TN, and re-irradiation has a major impact on the development of sensory disturbances after non-isocentric SRS. Interestingly, the integral dose may differ significantly in treatments using apparently similar dose and volume constraints.

Intramammary Infections in Heifers—Time of Onset and Associated Risk Factors (2020)

Nitz, Julia ; Krömker, Volker ; Klocke, Doris ; Wente, Nicole ; Zhang, Yanchao ; tho Seeth, Martin

To reduce the negative effects of mastitis in dairy heifers in early lactation on the future milking performance, the aim of this study was to define the time-related period of intramammary infections and to relate this to risk factors at heifer and quarter level for intramammary infections and subclinical mastitis. In total, 279 German Holstein Frisian heifers in three farms in Northern and Eastern Germany were included in this study. Quarter milk samples for cytomicrobiological examination were collected 3 +- 1 days after calving and 17 +- 3 days after calving, and risk factors at heifer and quarter level associated with intramammary infections and clinical mastitis were recorded during the trial period. Data were analyzed using logistic regression procedures and odds ratios were calculated. Calving at older ages increased the odds of intramammary infections with non-aureus staphylococci (NAS) and coryneforms 17 +- 3 days after calving compared to heifers calving at a younger age. Detaching of milking cups during milking is a risk factor for new infections between day 3 +- 1 and 17 +- 3 postpartum. The milk yield after calving is associated with a decrease in intramammary infections with environmental pathogens and clinical mastitis. A high milk yield assists the development of udder edema with an increased risk of intramammary infections with NAS and coryneforms. An increased somatic cell count (SCC) after calving increased the odds of intramammary infections with contagious pathogens 17 +- 3 days postpartum. The early lactation has an important influence on udder health and intramammary infections postpartum in dairy heifers. Udder quarters eliminated pathogens during early lactation by 6.9% for cases in this study. New infections manifest themselves up until 17 +- 3 days postpartum, especially with Corynebacterium spp. and NAS. In total, 82.9% of the infected quarters showed new infections with another pathogen species 17 +- 3 days postpartum than 3 +- 1 days postpartum. In conclusion, the early lactation has an important influence on udder health and intramammary infections postpartum in heifers with the possibility that udder quarters eliminate pathogens, but also the danger that new infections manifest themselves. Thus, the prevention of new infections by minimizing the associated risk factors is of great importance.

Simulation der Wirkung des Kabelschirms von PROFINET-Leitungen unter Berücksichtigung der Art der Schirmauflage (2020)

Otten, Jens Christian

Das Ziel dieser Bachelorarbeit ist es, ein einfach verständliches Simulationsmodell zur Darstellung der Wirkung von Kabelschirmen bei Betrachtung verschiedener Schirmauflageverfahren zu entwickeln. Die erarbeiteten Ergebnisse decken sich mit der allgemein vertretenen Meinung, dass die beste Schirmwirkung durch eine beidseitige und flächige Schirmauflage erzielt wird. Zuerst werden Grundlagen erklärt, wobei sich auf relevante Literatur bezogen wird. Daraus wird das Simulationsmodell hergeleitet, dessen Ergebnisse anhand von theoretischen Überlegungen und praktischen Messungen überprüft werden. Die vorliegende Arbeit ist interessant für Ingenieurinnen und Ingenieure der Automatisierungstechnik in der Prozess- und Fertigungsindustrie, die ein grundlegendes Verständnis für relevante Effekte der Kabelschirmung bilden wollen.

Einsatzgebiet und Wirksamkeit von Firewalls in Automatisierungssystemen unter besonderer Berücksichtigung von Next Generation Firewalls (2020)

Kühnlein, Marco

Zur Verbesserung der IT-Sicherheit im klassischen Büroumfeld wird bereits eine neue Firewall-Technologie, die sogenannte Next Generation Firewall verwendet. Um diese Technologie im Produktionsbereich einzusetzen, muss sie vorher getestet werden, da sich die Priorisierung der Schutzziele im Produktionsbereich und im Büroumfeld unterscheidet. In dieser Arbeit werden das Einsatzgebiet und die Wirkungsweise von Firewalls in industriellen Automatisierungssystemen im Allgemeinen und spezifisch für Next Generation Firewalls untersucht. Die Untersuchung geht auf die Aufgaben der einzelnen Firewalls in einem Produktionsunternehmen ein und prüft, welche Firewall durch eine Next Generation Firewall ergänzt werden kann. Dazu werden die konventionellen Firewall-Technologien mit der neuen Firewall-Technologie verglichen und bewertet. Der Nutzen der Next Generation Firewall in der Produktionsumgebung wird am Beispiel eines ausgewählten Angriffsszenarios erklärt. Abschließend werden Empfehlungen für dessen Einsatz in industriellen Automatisierungssystemen gegeben.

Manufacture of Hybrid Natural/Synthetic Fiber Woven Textiles for Use in Technical Biocomposites with Maximum Biobased Content (2019)

Shamsuyeva, Madina ; Winkelmann, Jana ; Endres, Hans-Josef

This feasibility study investigates the flexural properties of biocomposites containing woven flax textiles (plain, twill, satin) and woven twill patterned hybrid textiles containing flax-/glass or flax-/carbon mixture for lightweight applications. Synthetic fibers are integrated as weft and flax fibers are integrated as warp yarns using a double-rapier weaving machine with a Jacquard attachment. The corresponding biocomposites are manufactured via vacuum infusion process using a biobased epoxy resin as a matrix. The manufactured biocomposites are analyzed with regard to their density and flexural properties. The results show that the use of hybrid textiles offers a promising solution for the manufacture of biocomposites with a higher biobased content and significantly improved flexural properties. Furthermore, the introduction of high-performance synthetic fibers in textiles enables the manufacture of biocomposites with an isotropic mechanical performance.

Konzeption und Anwendung eines WordPress-Plugins für den Vergleich von Veranstaltungen (2020)

Fischer, Lukas

Plugins erweitern die Funktionalität von WordPress und helfen Webseitenbetreibern beim Hinzufügen neuer Elemente oder Funktionen. Dabei muss der Betreiber selbst keinen komplexen Programmcode schreiben. Auch können diese Erweiterungen als Erleichterung bei der Pflege von Informationen und Inhalten dienen. In der vorliegenden Bachelorarbeit wird die Konzipierung, Umsetzung und Anwendung eines solchen Plugins für den Vergleich von Veranstaltungen beschrieben. Dabei findet es Anwendung auf einer Internetseite zum Thema Festivals. Die Informationen bezüglich der Festivals werden per Import in einer Tabelle gespeichert und für den Vergleich dargestellt. Eintragungen können auch händisch getätigt werden, woraus sich schließlich ergibt, dass das Plugin mit seiner Importfunktion eine zeitsparende und sinnvolle Erweiterung ist.

Links between maternal postpartum depressive symptoms, maternal distress, infant gender and sensitivity in a high-risk population (2011)

Sidor, Anna ; Kunz, Elisabeth ; Schweyer, Daniel ; Eickhorst, Andreas ; Cierpka, Manfred

Background Maternal postpartum depression has an impact on mother-infant interaction. Mothers with depression display less positive affect and sensitivity in interaction with their infants compared to non-depressed mothers. Depressed women also show more signs of distress and difficulties adjusting to their role as mothers than non-depressed women. In addition, depressive mothers are reported to be affectively more negative with their sons than with daughters. Methods A non-clinical sample of 106 mother-infant dyads at psychosocial risk (poverty, alcohol or drug abuse, lack of social support, teenage mothers and maternal psychic disorder) was investigated with EPDS (maternal postpartum depressive symptoms), the CARE-Index (maternal sensitivity in a dyadic context) and PSI-SF (maternal distress). The baseline data were collected when the babies had reached 19 weeks of age. Results A hierarchical regression analysis yielded a highly significant relation between the PSI-SF subscale "parental distress" and the EPDS total score, accounting for 55% of the variance in the EPDS. The other variables did not significantly predict the severity of depressive symptoms. A two-way ANOVA with "infant gender" and "maternal postpartum depressive symptoms" showed no interaction effect on maternal sensitivity. Conclusions Depressive symptoms and maternal sensitivity were not linked. It is likely that we could not find any relation between both variables due to different measuring methods (self-reporting and observation). Maternal distress was strongly related to maternal depressive symptoms, probably due to the generally increased burden in the sample, and contributed to 55% of the variance of postpartum depressive symptoms.

Influence of early regulatory problems in infants on their development at 12 months: a longitudinal study in a high-risk sample (2013)

Sidor, Anna ; Fischer, Cristina ; Eickhorst, Andreas ; Cierpka, Manfred

Background: This study examined the extent to which regulatory problems in infants at 4 and 6 months influence childhood development at 12 months. The second aim of the study was to examine the influence maternal distress has on 4-month-old children’s subsequent development as well as gender differences with regard to regulatory problems and development. Methods: 153 mother-child dyads enrolled in the family support research project “Nobody slips through the net” constituted the comparison group. These families faced psychosocial risks (e.g. poverty, excessive demands on the mother, and mental health disorders of the mother, measured with the risk screening instrument Heidelberger Belastungsskala - HBS) and maternal stress, determined with the Parental Stress Index (PSI-SF). The children’s developmental levels and possible early regulatory problems were evaluated by means of the Ages and Stages Questionnaires (ASQ) and a German questionnaire assessing problems of excessive crying along with sleeping and feeding difficulties (SFS). Results: A statistically significant but only low, inverse association between excessive crying, whining and sleep problems at 4 and 6 months and the social development of one-year-olds (accounting for 5% and 8% of the variance respectively) was found. Feeding problems had no effect on development. Although regulatory problems in infants were accompanied by increased maternal stress level, these did not serve as a predictor of the child’s social development at 12 months. One-year-old girls reached a higher level of development in social and fine motor skills. No gender differences were found with regard to regulatory problems, nor any moderating effect of gender on the relation between regulatory problems and level of development. Conclusions: Our results reinforce existing knowledge pertaining to the transactional association between regulatory problems in infants, maternal distress and dysfunctionality of mother-child interactions. They also provide evidence of a slight but distinct negative influence of crying and sleeping problems on children’s subsequent social development. Easily accessible support services provided by family health visitors (particularly to the so-called “at-risk families”) are strongly recommended to help prevent the broadening of children’s early regulatory problems into other areas of behavior.

Hochverfügbare Automatisierungsnetzwerke am Beispiel von PROFINET (2020)

Stelljes, Sebastian ; Niemann, Karl-Heinz

Dieses Research Paper befasst sich mit dem Thema der Hochverfügbarkeit von Automatisierungsnetzwerken am Beispiel von PROFINET. Anhand von verschiedenen PROFINET-Topologien soll verdeutlicht werden, durch welche Maßnahmen eine hohe Verfügbarkeit erzielt werden kann. Zuvor wird mithilfe von grundliegenden Berechnungsbeispielen gezeigt, wie sich die Verfügbarkeit eines technischen Systems ermitteln lässt. Anschließend erfolgt für die Betrachtung der Gesamtverfügbarkeit einer PROFINET-Anlage eine genaue Bestimmung der jeweiligen Verfügbarkeitswerte für die einzelnen PROFINET-Geräte. Ein besonderes Augenmerk richtet sich hierbei speziell auf die Verwendung von IO Devices mit redundanten bzw. nicht-redundanten Interfacemodulen. Für das Erzielen einer hohen Verfügbarkeit sind nicht nur PROFINET-Geräte von entscheidender Bedeutung, sondern auch die Stuktur des PROFINET-Netzwerks. Im Zusammenspiel mit den bereits existierenden Redundanzprotokollen, die für die Verwaltung des Datenverkehrs zuständig sind, werden in diesem Bericht mehrere Topologien anhand verschiedener Eigenschaften und Voraussetzungen auf ihre Vor- und Nachteile untersucht und entsprechend ihrer Gesamtverfügbarkeitswerte bewertet. Dieses Research Paper basiert im Wesentlichen auf der Bachelorarbeit von Herrn Sebastian Stelljes an der Hochschule Hannover. Im Nachgang zur Arbeit wurden noch weitere Aspekte untersucht und mit den Inhalten der Bachelorarbeit zu diesem Research Paper zusammengeführt.

Oral cancer awareness among university students from Karachi, Pakistan (2019)

Limaye, Dnyanesh ; Ziesenis, Patrick ; Limaye, Vaidehi ; Ahmad, Mansoor ; Saeed, Farah ; Alam, Mahboob ; Rizvi, Ramla ; Kapadi, Atul ; Sathe, Sushama ; Fortwengel, Gerhard

Background: Oral cancers (OC) are malignant lesions occurring in the oral cavity that include squamous cell carcinomas (SCC), salivary gland and odontogenic neoplasms. Even though it is the eighth most common malignancy globally but in Pakistan it is the second commonest type of cancer. Lack of awareness about ill-effects of preventable risk factors of oral cancer increases the burden of disease due to the associated high cost of treatment, permanent impairment and high mortality. Hence, awareness can be very helpful in prevention, control and early diagnosis of oral cancer. Methods: A cross-sectional study was carried out among university students from Karachi, Pakistan during April to May 2018. Three hundred students were approached to participate in the study of which 277 agreed to participate. Pretested questionnaire was distributed and collected data was analysed using IBM SPSS version 23. Results: There were 125 (45%) males and 152 (55%) females in the study and response rate was 94%. Sixty one percent (154/250) respondents correctly identified smoking, and tobacco chewing as possible causes of oral cancer. Almost one third (74%; 184/250) respondents correctly responded that oral cancer does not spread from person to person through touch or speaking. Sixty six percent (164/250) respondents believed that oral cancer is curable. Mean score of knowledge was higher in females (61%) than males (53%). Significantly higher number of females compared to male participants answered correctly to questions regarding cause of oral cancer, spread of disease and occurrence of oral cancer in AIDS patients. Conclusions: Participants showed poor knowledge about oral cancer. Female participants showed better knowledge compared to male counterparts. Details about oral cancer should be incorporated in the university curriculum and periodic awareness programs should be organized for students.

Is the Brief Child Abuse Potential Inventory (BCAPI) a valid measure of child abuse potential among mothers and fathers of young children in Germany? (2019)

Liel, Christoph ; Meinck, Franziska ; Steinert, Janina I. ; Kindler, Heinz ; Lang, Katrin ; Eickhorst, Andreas

Background: In order to prevent child abuse, instruments measuring child abuse potential (CAP) need to be appropriate, reliable and valid. Objective: This study aimed to confirm the 6-factor structure of the Brief Child Abuse Potential Inventory (BCAPI) in a German sample of mothers and fathers, and to examine longitudinal predictors of CAP. Participants and setting: Two waves of data were collected from 197 mothers and 191 fathers of children aged 10–21 months for the “Kinder in Deutschland–KiD 0–3” in-depth study. Families were stratified based on prior self-report data for screening purposes. Methods: 138 fathers and 147 mothers were included in the analysis (invalid: 25% mothers, 30% fathers). First, validity of reporting was examined. Second, confirmatory factor analysis (CFA) was employed to assess factor structure. Third, internal reliability and criterion validity were examined. Finally, multivariate poisson regressions investigated longitudinal predictors of CAP in mothers. Results: A previously established six-factor structure was confirmed for mothers but not fathers. CFA failed for fathers due to large numbers of variables with zero variance. For mothers, internal consistency and criterion validity were good. BCAPI score at follow-up was associated with baseline BCAPI score (β= 00.08), stress (β= 0.06), education (β=-0.19) and alcohol use(β= .58). Conclusions: Findings confirm the six-factor structure of the BCAPI among German mothers. The clinical use of the BCAPI in fathers is not recommended as it might produce data that are hard to interpret. Further research with fathers is needed to establish if this is due to limitations with this dataset or with the questionnaire.

Perception of university students about doctors and quality of health care provision at clinics: a multi-national study in India, Pakistan, Spain and United States of America (2020)

Limaye, Dnyanesh ; Fortwengel, Gerhard ; Shankar Pitani, Ravi ; Sathe, Sushama ; Chivate, Sanika ; Jagadale, Prabhas ; Saeed, Farah ; Alam, Syed Mahboob ; Rodilla, Vicent ; Mounib, Chaimae ; Santiesteban Jr., Edel

Background: Patient satisfaction is considered as an indicator of the healthcare quality. Information on patient satisfaction based on medical expertise of the physician, interpersonal skills, physician-patient interaction time, perception and needs of the patient allow policymakers to identify areas for improvement. Primary care services and healthcare structure differ between the countries. The present study was done to determine and analyze the determinants associated with patient satisfaction in India, Pakistan, Spain and USA. Methods: This descriptive study was performed in January to August 2019 among students from Mumbai University, India, Dow University of Health Sciences, Karachi, Pakistan, University CEU Cardenal Herrera, Valencia, Spain, Texas State University, Texas, USA. On the basis of the eligibility criterion (those who gave a written informed consent and were registered students of respective university) 890 (India: 369, Pakistan: 128, Spain: 195, USA: 99) students were selected for the present study. Results: India had almost similar male (49%) to female (51%) ratio of participants. For other 3 countries (PK, ES, US), female participant percentage was nearly 20% or even more as compared to male participants. Overall participant’s satisfaction score about medial expertise of the doctor were highest in India (71%) and were lowest in Spain (43%). Overall satisfaction score about time spent with doctor were highest for India (64%) and were lowest for Spain (41%). Overall satisfaction score about communication with doctor were highest for US (60%) and were lowest for PK (53%). Overall satisfaction score for medical care given by the doctor was lowest in PK (43%) and was highest in US (64%). Overall satisfaction about doctor, highest number of US (83%) and lowest number of PK (32%) participants were satisfied about medical interaction with doctors. Conclusions: These multi-country findings can provide information for health policy making in India, Pakistan, Spain and USA. Although the average satisfaction per country, except Pakistan is more than 60%, the results suggest that there is ample room for improvement.

Knowledge, attitude and practices of antibiotic usage among university students from Karachi, Pakistan (2019)

Limaye, Dnyanesh ; Ziesenis, Patrick ; Limaye, Vaidehi ; Ahmad, Mansoor ; Saeed, Farah ; Rizvi, Ramla ; Kapadi, Atul ; Sathe, Sushama ; Fortwengel, Gerhard

Background: Antimicrobial resistance has become a serious global problem. A potential post-antibiotic era is threatening present and future medical advances. In Pakistan, the usage of antibiotic is unnecessarily high and due to over exposure to these drugs, bacteria are developing resistance against these drugs. It is necessary to improve public awareness about the rational use of antibiotics in order to bring a change in consumer’s behaviour. Therefore, present study was undertaken to assess the existing knowledge, attitude and practices related to antibiotic usage among university students. Methods: A cross-sectional study was carried out among university students from Karachi, Pakistan during May-June 2018. 200 students were approached to participate in the study of which 159 agreed to participate (males: 70, females: 89). Pretested questionnaire was distributed to the study subjects and the collected data was analyzed using IBM SPSS version 23. Results: Substantial number of (33% and 50%) participants were unaware about the differences in antibiotic: anti-inflammatory drugs and antibiotic: antipyretics respectively. 29% of the participants thought it is right to stop antibiotics only based on symptomatic improvement. Thirty nine percent and eighty three percent participants believed that antibiotics should always be prescribed to treat flu like symptoms and pneumonia respectively. Conclusions: Participants demonstrated average knowledge about antibiotics. Similarly, their attitude and practice toward antibiotic use was associated with misconceptions. An educational intervention is necessary to make them aware about rational use of antibiotics.

Expectancy, usage and acceptance by general practitioners and patients: exploratory results from a study in the German outpatient sector (2017)

Albrecht, Urs-Vito ; Afshar, Kambiz ; Illiger, Kristin ; Becker, Stefan ; Hartz, Tobias ; Breil, Bernhard ; Wichelhaus, Daniel ; von Jan, Ute

Objective: The study’s objective was to assess factors contributing to the use of smart devices by general practitioners (GPs) and patients in the health domain, while specifically addressing the situation in Germany, and to determine whether, and if so, how both groups differ in their perceptions of these technologies. Methods: GPs and patients of resident practices in the Hannover region, Germany, were surveyed between April and June 2014. A total of 412 GPs in this region were invited by email to participate via an electronic survey, with 50 GPs actually doing so (response rate 12.1%). For surveying the patients, eight regional resident practices were visited by study personnel (once each). Every second patient arriving there (inclusion criteria: of age, fluent in German) was asked to take part (paper-based questionnaire). One hundred and seventy patients participated; 15 patients who did not give consent were excluded. Results: The majority of the participating patients (68.2%, 116/170) and GPs (76%, 38/50) owned mobile devices. Of the patients, 49.9% (57/116) already made health-related use of mobile devices; 95% (36/38) of the participating GPs used them in a professional context. For patients, age (P<0.001) and education (P<0.001) were significant factors, but not gender (P>0.99). For doctors, neither age (P¼0.73), professional experience (P>0.99) nor gender (P¼0.19) influenced usage rates. For patients, the primary use case was obtaining health (service)-related information. For GPs, interprofessional communication and retrieving information were in the foreground. There was little app-related interaction between both groups. Conclusions: GPs and patients use smart mobile devices to serve their specific interests. However, the full potentials of mobile technologies for health purposes are not yet being taken advantage of. Doctors as well as other care providers and the patients should work together on exploring and realising the potential benefits of the technology.

A study to assess knowledge and attitude towards HIV among students from Mumbai university (2019)

Limaye, Dnyanesh ; Fortwengel, Gerhard ; Limaye, Vaidehi ; Bhasi, Aishwarya ; Dhule, Aditya ; Dugane, Rajesh ; Borkar, Asang ; Shankar Pitani, Ravi ; Sathe, Sushama ; Kapadi, Atul

Background: India has the third largest HIV epidemic in the world. The Indian epidemic is characterized by low levels in the general population and elevated concentrations among high-risk groups. The present study was planned to determine the awareness of HIV among students from Mumbai University. Methods: A cross-sectional study was carried out among students from Mumbai University, India during May–June 2017. Two hundred and fifty students were approached to participate in the study of which 199 agreed to participate (males: 132; females: 67). Pretested questionnaire was distributed and collected data was analyzed using IBM SPSS version 23. Results: Study participants had high knowledge (86%) and attitude score (87%). There was no significant difference between males and female participants for attitude and knowledge, except for one question regarding knowledge about HIV transmission via breastfeeding to child. Conclusions: Present study showed that there are no misconceptions or negative attitudes regarding HIV among students. A longitudinal study with a larger sample size across India is recommended for further investigation.

Politicians’ Self-Reported Social Media Activities (2019)

Kelm, Ole ; Dohle, Marco ; Bernhard, Uli

The growing importance of social media in the political arena seems to be in line with the mediatization of politics thesis, which states that mediated communication is becoming more important in politics and increasingly influences political processes. However, how politicians’ social media activities and politicians’ perceptions concerning social media have developed over time has rarely been examined. Moreover, it is unclear how the politicians’ activities and perceptions are related to each other. Referring to theoretical approaches, such as the influence of presumed influence approach, four surveys were conducted among German parliamentarians (MPs) between 2012 and 2016 (n = 194/149/170/118). The results indicate that the MPs’ self-reported social media activities and perceptions have remained remarkably constant since 2012. Regression analyses indicate that MPs’ self-reported social media activities and perceptions are hardly related to each other. This raises the question whether mediatization processes are indeed driven by politicians’ perceptions about media influences.

Knowledge, attitude and practices of antibiotic usage among students from Mumbai University (2018)

Limaye, Dnyanesh ; Naware, Sanika ; Bare, Priyanka ; Dalvi, Shreya ; Dhurve, Ketaki ; Sydymanov, Arlan ; Limaye, Vaidehi ; Shankar Pitani, Ravi ; Kanso, Zeinab ; Fortwengel, Gerhard

Background: Discovery of antibiotics have helped to manage the devastating diseases. Presently, the antibiotic era is threatened by the emergence of high level of antibiotic resistance of important pathogens. Misuse of antibiotics poses a serious risk to infectious disease control. It is necessary to improve public awareness to bring a change in the behavior of consumers. Therefore, present study was undertaken to assess the existing knowledge, attitude and practices related to antibiotic usage among university students. Methods: A cross-sectional study was carried out among students from Mumbai University, India during May-June 2017. 300 students were approached to participate in the study of which 250 agreed to participate (males: 117; females: 133). Pretested questionnaire was distributed and collected data was analyzed using IBM SPSS version 23. Results: Substantial number (33% and 40%) participants were unaware about the differences in antibiotic-anti-inflammatory drugs and antibiotic-antipyretics respectively. 28% of the participants thought it is right to stop antibiotics only based on symptoms improvement. Sixty eight percent and seventy nine percent participants believed that antibiotics should always be prescribed to treat flu like symptoms and pneumonia respectively. Conclusions: Participants demonstrated poor knowledge about antibiotics. Similarly, their attitude and practice toward antibiotic use was associated with misconceptions. An educational intervention can be introduced to make them aware about rational antibiotic practices.

Integrierte softwaregestützte Sicherheitsanalyse von Automatisierungsanlagen (INSA) (2016)

Tebbe, Christopher ; Glawe, Matthias ; Niemann, Karl-Heinz ; Fay, Alexander ; Dittgen, Josha ; Eckardt, Jörg

Im Rahmen des vom Bundesministerium für Wirtschaft und Technologie geförderten Forschungsprojektes INSA sollen wichtige Beiträge zur Verbesserung der IT-Sicherheit von Produktionsanlagen insbesondere in kleinen und mittelständischen Unternehmen (KMU) realisiert und erprobt werden. Die IT-Sicherheit von Produktionsanlagen wird zu einer immer wichtigeren Komponente des Schutzes von Unternehmen gegen Cyber-Attacken. Neben Angriffen aus dem Internet sind dabei interne Angriffsquellen in Betracht zu ziehen. Gängige Vorgehensmodelle, wie z. B. die VDI-Richtlinie 2182, setzen dabei unter anderem auf eine wiederkehrende Analyse der Bedrohungen und auf die Implementierung entsprechender Schutzmaßnahmen. Die Durchführung einer solchen wiederkehrenden Gefährdungsanalyse ist mit einem wiederkehrenden manuellen Aufwand verbunden, weshalb kleine und mittlere Unternehmen die Durchführung dieser Maßnahmen häufig meiden. Ziel des Projektes ist die Unterstützung kleiner und mittlerer Unternehmen bei der Durchführung entsprechender Bedrohungsanalysen zu unterstützen. Der Ansatz des Projektes beruht auf der automatisierten bzw. teilautomatisierten Erfassung der installierten Automatisierungskomponenten (Assets). Danach kann für bekannte Standardkomponenten durch die Verwendung wissensbasierter Methoden eine Beurteilung der Bedrohung einer Automatisierungsanlage erfolgen. Hierfür wird fachspezifisches Wissen erfasst und verarbeitet wird. Diese Methoden können bei Bedarf in die Engineering-Oberfläche einer Automatisierungsanlage intergiert werden.

Co2rona Effekt - Sektorspezifische Betrachtung in Deutschland 2020 (2020)

Alfeis, Lisa-Marie ; Deierling, Pascal ; Gödecke, Timo ; Mevers, Sebastian ; Zimmermann, Tobias ; Andres, Sven Frederic ; Bedrunka, Alexander ; Lüdersen, Ulrich

Die folgende Studie befasst sich mit den Auswirkungen der Corona-Pandemie und deren Effekt – ein verminderter CO2-Ausstoß in Deutschland. Für einen übersichtlichen Vergleich wird im weiteren Verlauf in unterschiedlichen Szenarien darauf eingegangen, wie sich der CO2-Ausstoß im Vergleich zu 2020 ohne die Corona-Pandemie in Deutschland verändern könnte. Grundbasis für die Ermittlungen der folgenden Szenarien ist der CO2-Trend ohne die Corona-Pandemie im Jahr 2020, in dem Deutschland das Emissionsziel von -40 % gegenüber 1990 mit einer Reduktion von lediglich 37 % verfehlt hätte. Im zweiten Szenario wird dargestellt, wie sich die aktuelle Corona-Pandemie mit verschiedenen Lockdown-Phasen auf den CO2-Ausstoß auswirkt. Deutlich wird hierbei, dass trotz der aktuellen Maßnahmen eine längere Lockdown-Phase benötigt wird, um das Klimaziel von -40 % langfristig gesichert zu erreichen. In den Szenarien 3 und 4 liegt der Fokus auf möglichen Handlungs- und Verhaltensweisen nach der Pandemie. Das Szenario 3 betrachtet die Folgen von wirtschaftsfördernden Maßnahmen nach dem Lockdown und dem damit einhergehenden CO2-Anstieg. Wie viel CO2 zusätzlich aufgrund von nachhaltigem und klimaorientiertem Verhalten eingespart werden kann, erläutert das Szenario 4 „CO2 Entwicklung unter Berücksichtigung der Corona-Pandemie 2020 und möglicher positiver Umweltentwicklungen aus dem Lockdown“. Faktoren, wie die wachsende Bevölkerung, sich verändernde Produktionsfaktoren oder Umwelteinflüsse wurden vernachlässigt. Die Studie zeigt, dass die Chancen, die durch die wirtschaftlichen Einschnitte und die Verhaltensänderungen, die durch die Corona-Pandemie bzw. deren Folgen hervorgerufen wurden, einen maßgeblichen Einfluss auf den CO2-Ausstoß der Bundesrepublik Deutschland haben können.

The benefits of agreeing on what matters most: Team cooperative norms mediate the effect of co-leaders' shared goals on safety climate in neonatal intensive care units (2018)

Kuntz, Ludwig ; Scholten, Nadine ; Wilhelm, Hendrik ; Wittland, Michael ; Hillen, Hendrik Ansgar

BACKGROUND: Safety climate research suggests that a corresponding climate in work units is crucial for patient safety. Intensive care units are usually co-led by a nurse and a physician, who are responsible for aligning an interprofessional workforce and warrant a high level of safety. Yet, little is known about whether and how these interprofessional co-leaders jointly affect their unit's safety climate. PURPOSE: This empirical study aims to explain differences in the units' safety climate as an outcome of the nurse and physician leaders' degree of shared goals. Specifically, we examine whether the degree to which co-leaders share goals in general fosters a safety climate by pronouncing norms of interprofessional cooperation as a behavioral standard for the team members' interactions. METHODOLOGY/APPROACH: A cross-sectional design was used to gather data from 70 neonatal intensive care units (NICUs) in Germany. Survey data for our variables were collected from the unit's leading nurse and the leading physician, as well as from the unit's nursing and physician team members. Hypotheses testing at unit level was conducted using multivariate linear regression. RESULTS: Our analyses show that the extent to which nurse-physician co-leaders share goals covaries with safety climate in NICUs. This relationship is partially mediated by norms of interprofessional cooperation among NICU team members. Our final model accounts for 54% of the variability in safety climate of NICUs. CONCLUSION: Increasing the extent to which co-leaders share goals is an effective lever to strengthen interprofessional cooperation and foster a safety climate among nursing and physician team members of hospital units.

Modified ‘Stable Schools’ as a Consulting Tool for Organic Dairy Herds (2020)

Hansmann, Verena ; Volling, Otto ; Krömker, Volker

The aim of this study was to examine the opinions of farmers on a consulting project, which was established for organic dairy farms in Northern Germany involving different animal health experts who participated in the meetings. Furthermore, the properties of measures that are of decisive importance for implementation on the farms were identified to improve consultancy services for dairy farming. Once a year, the farmers met on a host-farm in one of three groups consisting of five to nine farms, a facilitator and an expert. At each meeting, a host-farm was visited and the analysed data of all participating farms of the previous year were presented to the group members. Each farmer had the possibility to report on success stories and issues concerning his herd. During discussions, the farmers first proposed mutual farm-specific measures for improving herd health and animal welfare. Afterwards, the expert named possible interventions and commented on the given measures of the farmers. All measures were noted by the facilitator. At the end of each meeting, each farmer could choose which of the given measures he wanted to implement. Open group-interviews as well as anonymous questionnaires for the farmers were used at the meetings in winter 2016/2017 to evaluate their perception of this consulting project and to determine which properties of measures were important for implementation on the farms. Based on the results of this study, the participating farmers were very positive towards this kind of consulting project. They favoured the participation of an expert during the meetings and the analysis of farm-specific data. Farmers mostly chose measures for implementation proposed by farmers and approved by the expert, followed by those proposed by the expert only. Measures were chosen when they were practical in the implementation, effective, efficient and took a low additional workload for implementation.

Case-control study on factors associated with a decreased milk yield and a depressed health status of dairy herds in northern Germany (2019)

Jensen, Katharina Charlotte ; Frömke, Cornelia ; Schneider, Bettina ; Do Duc, Phuong ; Gundling, Frieder ; Birnstiel, Katrin ; Schönherr, Franziska ; Scheu, Theresa ; Kaiser-Wichern, Anika ; Woudstra, Svenja ; Seyboldt, Christian ; Hoedemaker, Martina ; Campe, Amelie

Background In the past years, it became apparent that health status and performance differ considerably within dairy farms in Northern Germany. In order to obtain clues with respect to possible causes of these differences, a case-control study was performed. Case farms, which showed signs of health and performance problems, and control farms, which had none of these signs, were compared. Risk factors from different areas such as health management, housing, hygiene and nutrition were investigated as these are known to be highly influential. The aim of this study was to identify major factors within these areas that have the strongest association with health and performance problems of dairy herds in Northern Germany. Results In the final model, a lower energy density in the roughage fraction of the diet, more pens with dirty lying areas and a low ratio of cows per watering spaces were associated with a higher risk for herd health problems. Moreover, case farms were affected by infections with intestinal parasites, lungworms, liver flukes and Johne’s Disease numerically more often than control farms. Case farms more often had pens with raised cubicles compared to the deep bedded stalls or straw yards found in control farms. In general, the hygiene of the floors and beddings was worse in case farms. Concerning nutrition, the microbiological and sensory quality of the provided silages was often insufficient, even in control farms. Less roughage was provided to early lactating cows and the feed was pushed to the feeding fence less frequently in case farms than in control farms. Conclusions The results show that milk yield and health status were associated with various factors from different areas stressing the importance of all aspects of management for good animal health and performance. Moreover, this study confirmed well-known risk factors for health problems and performance losses. These should better be taken heed of in herd health management.

A systematic scorecard-based approach to site assessment in preparation for Lassa fever vaccine clinical trials in affected countries (2020)

Salami, Kolawole ; Imbault, Nathalie ; Erlebach, Aljoscha ; Urban, Johanna ; Zoglowek, Mike ; Tornieporth, Nadia G.

Background: We sought to develop and test an objective scorecard-based system for assessing and categorizing available research sites in Lassa fever-affected countries based on their preparedness and capability to host Lassa fever vaccine clinical trials. Methods: We mapped available clinical research sites through interrogation of online clinical trial registries and relevant disease-based consortia. A structured online questionnaire was used to assess the capability of clinical trial sites to conduct Lassa fever vaccine clinical trials. We developed a new scoring template by allocating scores to questionnaire parameters based on perceived importance to the conduct of clinical trials as described in the WHO/TDR Global Competency Framework for Clinical Research. Cutoff points of 75% and 50% were used to categorize sites into categories A, B, or C. Results: This study identified 44 clinical trial sites in 8 Lassa fever-affected countries. Out of these, 35 sites were characterized based on their capacity to hold Lassa fever vaccine clinical trials. A total of 14 sites in 4 countries were identified as ready to host Lassa fever vaccine trials immediately or with little support. Conclusion: It is feasible to hold Lassa fever vaccine trials in affected countries based on the outcome of the survey. However, the findings are to be validated through sites' visits. This experience with a standardized and objective method of the site assessment is encouraging, and the site selection method used can serve as an orientation to sponsors and researchers planning clinical trials in the region.

Noise patterns in visceral surgical procedures: Analysis of second-bysecond dBA data of 599 procedures over the course of one year (2020)

Baltin, Christoph Tobias ; Wilhelm, Hendrik ; Wittland, Michael ; Hölscher, Arnulf H. ; Stippel, Dirk ; Astvatsatourov, Anatoli

The objective of this study is to analyze noise patterns during 599 visceral surgical procedures. Considering work-safety regulations, we will identify immanent noise patterns during major visceral surgeries. Increased levels of noise are known to have negative health impacts. Based on a very finegrained data collection over a year, this study will introduce a new procedure for visual representation of intra-surgery noise progression and pave new paths for future research on noise reduction in visceral surgery. Digital decibel sound-level meters were used to record the total noise in three operating theatres in one-second cycles over a year. These data were matched to archival data on surgery characteristics. Because surgeries inherently vary in length, we developed a new procedure to normalize surgery times to run cross-surgery comparisons. Based on this procedure, dBA values were adjusted to each normalized time point. Noise-level patterns are presented for surgeries contingent on important surgery characteristics: 16 different surgery types, operation method, day/night time point and operation complexity (complexity levels 1–3). This serves to cover a wide spectrum of day-to-day surgeries. The noise patterns reveal significant sound level differences of about 1 dBA, with the mostcommon noise level being spread between 55 and 60 dBA. This indicates a sound situation in many of the surgeries studied likely to cause stress in patients and staff. Absolute and relative risks of meeting or exceeding 60 dBA differ considerably across operation types. In conclusion, the study reveals that maximum noise levels of 55 dBA are frequently exceeded during visceral surgical procedures. Especially complex surgeries show, on average, a higher noise exposure. Our findings warrant active noise management for visceral surgery to reduce potential negative impacts of noise on surgical performance and outcome.

Antimicrobial Activity of a Phage Mixture and a Lactic Acid Bacterium against Staphylococcus aureus from Bovine Mastitis (2020)

Titze, Isabel ; Krömker, Volker

The antimicrobial activity of a phagemixture and a lactic acid bacteriumagainst Staphylococcus aureus isolates from bovine origin was investigated in vitro with regard to possible applications in the therapy of udder inflammation (mastitis) caused by bacterial infections. The S. aureus isolates used for inoculation derived from quarter foremilk samples of mastitis cases. For the examination of the antimicrobial activity, the reduction of the S. aureus germ density was determined [log10 cfu/mL]. The phage mixture consisted of the three obligatory lytic and S. aureus-specific phages STA1.ST29, EB1.ST11 and EB1.ST27 (1:1:1). The selected Lactobacillus plantarum strain with proven antimicrobial properties and the phage mixture were tested against S. aureus in milk, both alone and in combination. The application of the lactic acid bacterium showed only a low reduction ability for a 24 h incubation period. The bacteriophage mixture as well as its combination with the lactic acid bacterium showed high antimicrobial activity against S. aureus for a 24 h incubation period at 37 C, with only the phage mixture showing significance.

Prevention of Intramammary Infections by Prepartum External Application of a Teat Dip Containing Lactic Acid Bacteria with Antimicrobial Properties in Dairy Heifers (2020)

Paduch, Jan-Hendrik ; Lücking, Johanna ; Mansion-de Vries, Elisabeth ; Zinke, Claudia ; Wente, Nicole ; Krömker, Volker

The aim of the current study was to investigate the effects of the prepartum external treatment of teats with a combination of four lactic acid bacteria strains viz. Lactobacillus (Lb.) rhamnosus ATCC 7469, Lactococcus lactis subsp. lactis ATCC 11454, Lb. paracasei 78/37 (DSM 26911), and Lb. plantarum 118/37 (DSM 26912) on the postcalving udder health of dairy heifers. The study used a split-udder design. Two weeks before the expected calving date, one of two contralateral teats of a teat pair was dipped with an aqueous suspension of lactic acid bacteria (final bacterial counts 8.40–8.47 log10-transformed CFU/mL) once in a week until calving; the other teat of the pair was not treated. After calving, quarter foremilk samples were taken and investigated cyto-microbiologically. In total, 629 teat pairs of 319 heifers were included. There was an association between the treatment and intramammary infections caused by the major udder-pathogenic bacteria Staphylococcus aureus, Streptococcus dysgalactiae, and enterococci, as well as clinical mastitis in the first 100 days after calving. The present study indicates that intramammary infections with major pathogens and clinical mastitis may be prevented by regular prepartum external application of lactic acid bacteria in dairy heifers.

An Approach to Calculate and Visualize Intraoperative Scattered Radiation Exposure (2009)

Wagner, Markus ; Duwenkamp, Christopher ; Dresing, Klaus ; Bott, Oliver J.

During the intraoperative radiograph generation process with mobile image intensifier systems (C-arm) most of the radiation exposure for patient, surgeon and operation room personal is caused by scattered radiation. The intensity and propagation of scattered radiation depend on different parameters, e.g. the intensity of the primary radiation, and the positioning of the mobile image intensifier. Exposure through scattered radiation can be minimized when all these parameters are adjusted correctly. Because radiation is potentially dangerous and could not be perceived by any human sense the current education on correct adjustment of a C-arm is designed very theoretical. This paper presents an approach of scattered radiation calculation and visualization embedded in a computer based training system for mobile image intensifier systems called virtX. With the help of this extension the virtX training system should enrich the current radiation protection training with visual and practical training aspects.

Results of a Literature Review to Prepare Data Modelling in the Context of Kidney Transplant Rejection Diagnosis (2019)

Katzensteiner, Matthias ; Ludwig, Wolfram ; Marschollek, Michael ; Bott, Oliver J.

Due to demographic change the number of serious kidney diseases and thus required transplantations will increase. The increased demand for donor organs and a decreasing supply of these organs underline the necessity for effective early rejection diagnostic measures to improve the lifetime of transplants. Expert systems might improve rejection diagnostics but for the development of such systems data models are needed that encompass the relevant information to enable optimal data aggregation and evaluation. Results of a literature review concerning published data models and information systems concerned with kidney transplant rejection diagnostic lead to a set of data elements even if no papers could be identified that publish data models explicitly.

Using openEHR Archetypes for Automated Extraction of Numerical Information from Clinical Narratives (2019)

Zubke, Maximilian ; Bott, Oliver J. ; Marschollek, Michael

Up to 80% of medical information is documented by unstructured data such as clinical reports written in natural language. Such data is called unstructured because the information it contains cannot be retrieved automatically as straightforward as from structured data. However, we assume that the use of this flexible kind of documentation will remain a substantial part of a patient’s medical record, so that clinical information systems have to deal appropriately with this type of information description. On the other hand, there are efforts to achieve semantic interoperability between clinical application systems through information modelling concepts like HL7 FHIR or openEHR. Considering this, we propose an approach to transform unstructured documented information into openEHR archetypes. Furthermore, we aim to support the field of clinical text mining by recognizing and publishing the connections between openEHR archetypes and heterogeneous phrasings. We have evaluated our method by extracting the values to three openEHR archetypes from unstructured documents in English and German language.

Familiär im Norden – Nachlese zur 26. BOBCATSSS in Riga, Lettland (2018)

Blümel, Ina ; Clausing, Silke ; Altemeier, Franziska ; Andresen, Amelie ; Brun, Aline ; Dony, Carina ; Kaminski, Marisa ; Pellowski, Antje ; Schugt, Helena ; Talk, Anne

Bereits zum dritten Mal in Folge nahm eine zehnköpfige Gruppe Studierender der Hochschule Hannover aus dem Vollzeit- sowie dem berufsbegleitenden Bachelor-Studiengang Informationsmanagement, in Begleitung zweier Dozentinnen, an der BOBCATSSS-Konferenz teil. Nachdem bisher ausschließlich auf der Hochschulwebseite und tagesaktuell im Blog über Erfahrungen und Erlebnisse während der drei BOBCATSSS-Exkursionen berichtet wurde, folgt hiermit nun ein zusammenhängender Beitrag über die diesjährige Konferenz vom 24. bis zum 26. Januar 2018 in Riga, Lettland. Die BOBCATSSS-Konferenz ist eine internationale Konferenz der Bibliotheks- und Informationswissenschaften. Im Gegensatz zu IFLA & Co wird sie fast ausschließlich von Studierenden wechselnder Universitäten in Europa ausgerichtet.

Vergleich von nativer App- und Cross-Platform-Entwicklung (Facebook React Native und Google Flutter) (2020)

Armagan, Ferdi

Die Entwicklung mobiler Applikationen für iOS und Android ist in der Regel mit viel Arbeit verbunden, da man für beide Plattformen gezwungenermaßen unterschiedlichen Quelltext schreiben muss. Abhilfe für dieses Problem schaffen Cross-Platform-Frameworks wie React Native von Facebook oder Flutter von Google. Anhand dieser Frameworks lassen sich Apps für beide Plattformen mit nur einer Codebase entwickeln. Eine kritische Stelle und oft gebrauchtes Kontra-Argument gegen die Entwicklung mit Cross-Platform-Frameworks ist die Hardwarenähe der nativen Applikationen, an welcher es den Frameworks vermeintlich mangelt. Doch wie ist der Stand der Dinge im Jahr 2020? Können Cross-Platform-Frameworks inzwischen performant und einfach auf Hardwarekomponenten zugreifen und machen damit die mühsame, native Entwicklung für iOS und Android vor allem in Anbetracht der Entwicklung von größerer Enterprise-Software obsolet? Dieser Frage wird in dieser Arbeit nachgegangen und generell überprüft wie tauglich die Cross-Platform-Entwicklung ist. Nach dem Lesen dieser Bachelorarbeit sollte entschieden werden können, ob Cross-Platform-Frameworks für das Anwendungsproblem des Lesers geeignet sind. Um die Forschungsfrage zu beantworten, wurden je zwei Applikationen im Rahmen einer Fallstudie für je iOS und Android entwickelt, damit geprüft werden konnte, wie förderlich die zuvor genannten Frameworks sind. Der Fokus der Arbeit liegt also auf der Güte bzw. dem heutigen Stand der Cross-Platform-Entwicklung, vor allem im Bezug auf die Benutzung von Hardwarekomponenten bzw. betriebssystemspezifischen Diensten (Bluetooth, Kamera, etc.). Die Ergebnisse der Fallstudie zeigen, dass es stets auf den Kontext und die Komplexität der zu realisierenden Anwendung ankommt inwiefern Cross-Platform-Frameworks verwendet werden können. In simplen Anwendungsfällen können Frameworks meist zu einer erheblichen Kostenminimierung und Zeitersparnis führen, wohingegen bei komplexeren Anwendungen relativ schnell Grenzen und starke Abhängigkeiten erreicht werden.

Electrospun Polyacrylonitrile Based Carbon Nanofibers: The Role of Creep Stress towards Cyclization and Graphitization (2018)

Bin Ali, Annas ; Dreyer, Bastian ; Renz, Franz ; Tegenkamp, Christoph ; Sindelar, Ralf

The properties of these carbon nanostructures are determined by the structure and orientation of the graphitic domains during pyrolysis of carbon precursors. In this work, we investigated systematically the impact of creep stress during the stabilization process on the cyclization and molecular orientation of polyacrylonitrile as well as the graphitized structure after high temperature carbonization. Therefore, polyacrylonitrile (PAN) is electrospun and then stabilized with and without application of creep stress at different temperatures. The effect of creep stress on cyclization was monitored via Fourier transform IR spectroscopy (FTIR) and it was found that the degree of cyclization varies with the application of creep stress during the initial stages of cyclization at low temperatures (190°C and 210°C) in contrast to cyclization done at higher temperature (230°C). Herman molecular orientation factor was evaluated by polarized FTIR for PAN nanofibers cyclized with and without creep stress at 230°C-10 h. Subsequently, carbonization was performed at 1000°C and 1200°C for nanofibers cyclized at 230°C-10 h. Our results from XRD and Raman spectroscopy shows that the degree of graphitization and ordering of graphitic domains was enhanced for PAN nanofibers that were creep stressed during the cyclization process, even though both PAN nanofibers cyclized with creep stress and without creep stress showed the same amount of cyclized material. This increased degree of graphitization can be tracked to application of creep stress during the stabilization process which obviously

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