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Return to work after ischemic stroke in young adults : A registry-based follow-up study (2018)

Aarnio, Karoliina ; Rodríguez-Pardo, Jorge ; Siegerink, Bob ; Hardt, Juliane ; Broman, Jenna ; Tulkki, Lauri ; Haapaniemi, Elena ; Kaste, Markku ; Tatlisumak, Turgut ; Putaala, Jukka

Objective We aimed to investigate the proportion of young patients not returning to work (NRTW) at 1 year after ischemic stroke (IS) and during follow-up, and clinical factors associated with NRTW. Methods Patients from the Helsinki Young Stroke Registry with an IS occurring in the years 1994–2007, who were at paid employment within 1 year before IS, and with NIH Stroke Scale score ≤15 points at hospital discharge, were included. Data on periods of payment came from the Finnish Centre for Pensions, and death data from Statistics Finland. Multivariate logistic regression analyses assessed factors associated with NRTW 1 year after IS, and lasagna plots visualized the proportion of patients returning to work over time. Results We included a total of 769 patients, of whom 289 (37.6%) were not working at 1 year, 323 (42.0%) at 2 years, and 361 (46.9%) at 5 years from IS. When adjusted for age, sex, socioeconomic status, and NIH Stroke Scale score at admission, factors associated with NRTW at 1 year after IS were large anterior strokes, strokes caused by large artery atherosclerosis, high-risk sources of cardioembolism, and rare causes other than dissection compared with undetermined cause, moderate to severe aphasia vs no aphasia, mild and moderate to severe limb paresis vs no paresis, and moderate to severe visual field deficit vs no deficit. Conclusions NRTW is a frequent adverse outcome after IS in young adults with mild to moderate IS. Clinical variables available during acute hospitalization may allow prediction of NRTW.

Automatic Identification of Synonym Relations in the Dutch Parliament’s Thesaurus (2017)

Aga, Rosa Tsegaye ; Wartena, Christian ; Lange, Otto ; Aders, Nelleke

For indexing archived documents the Dutch Parliament uses a specialized thesaurus. For good results for full text retrieval and automatic classification it turns out to be important to add more synonyms to the existing thesaurus terms. In the present work we investigate the possibilities to find synonyms for terms of the parliaments thesaurus automatically. We propose to use distributional similarity (DS). In an experiment with pairs of synonyms and non-synonyms we train and test a classifier using distributional similarity and string similarity. Using ten-fold cross validation we were able to classify 75% of the pairs of a set of 6000 word pairs correctly.

A multicenter, randomized, open-labeled study to steer immunosuppressive and antiviral therapy by measurement of virus (CMV, ADV, HSV)-specific T cells in addition to determination of trough levels of immunosuppressants in pediatric kidney allograft recipients (IVIST01-trial): study protocol for a randomized controlled trial (2014)

Ahlenstiel-Grunow, Thurid ; Koch, Armin ; Großhennig, Anika ; Frömke, Cornelia ; Sester, Martina ; Sester, Urban ; Schröder, Christoph ; Pape, Lars

Background: After kidney transplantation, immunosuppressive therapy causes impaired cellular immune defense leading to an increased risk of viral complications. Trough level monitoring of immunosuppressants is insufficient to estimate the individual intensity of immunosuppression. We have already shown that virus-specific T cells (Tvis) correlate with control of virus replication as well as with the intensity of immunosuppression. The multicentre IVIST01-trial should prove that additional steering of immunosuppressive and antiviral therapy by Tvis levels leads to better graft function by avoidance of over-immunosuppression (for example, viral infections) and drug toxicity (for example, nephrotoxicity). Methods/design: The IVIST-trial starts 4 weeks after transplantation. Sixty-four pediatric kidney recipients are randomized either to a non-intervention group that is only treated conservatively or to an intervention group with additional monitoring by Tvis. The randomization is stratified by centre and cytomegalovirus (CMV) prophylaxis. In both groups the immunosuppressive medication (cyclosporine A and everolimus) is adopted in the same target range of trough levels. In the non-intervention group the immunosuppressive therapy (cyclosporine A and everolimus) is only steered by classical trough level monitoring and the antiviral therapy of a CMV infection is performed according to a standard protocol. In contrast, in the intervention group the dose of immunosuppressants is individually adopted according to Tvis levels as a direct measure of the intensity of immunosuppression in addition to classical trough level monitoring. In case of CMV infection or reactivation the antiviral management is based on the individual CMV-specific immune defense assessed by the CMV-Tvis level. Primary endpoint of the study is the glomerular filtration rate 2 years after transplantation; secondary endpoints are the number and severity of viral infections and the incidence of side effects of immunosuppressive and antiviral drugs. Discussion: This IVIST01-trial will answer the question whether the new concept of steering immunosuppressive and antiviral therapy by Tvis levels leads to better future graft function. In terms of an effect-related drug monitoring, the study design aims to realize a personalization of immunosuppressive and antiviral management after transplantation. Based on the IVIST01-trial, immunomonitoring by Tvis might be incorporated into routine care after kidney transplantation.

Usability Testing of Visual Policy Evaluation for Network Security Event Detection (2020)

Ahlers, Volker ; Hellmann, Bastian

The network security framework VisITMeta allows the visual evaluation and management of security event detection policies. By means of a "what-if" simulation the sensitivity of policies to specific events can be tested and adjusted. This paper presents the results of a user study for testing the usability of the approach by measuring the correct completion of given tasks as well as the user satisfaction by means of the system usability scale.

Effects of exercise training on bone mineral density and some health-related outcomes in HIV conditions : A randomized controlled trial (2020)

Ajidahun, Adedayo Tunde ; Myezwa, Hellen ; Ibeneme, Sam Chidi ; Magobotha, Sebastian ; Fortwengel, Gerhard ; Jingo, Maxwell ; Milner, Brenda ; Ravat, Sadiya ; Okoye, Ifeoma ; Schnaid, Edward ; Bischoff, Faith

Introduction: Human Immunodeficiency Virus (HIV) infection remains prevalent co-morbidity, and among fracture patients. Few studies have investigated the role of exercise interventions in preventing bone demineralization in people who have fractures and HIV. If exercise exposed, HIV-infected individuals may experience improved bone health outcomes (BMD), function, quality of life (QoL). The study will aim to assess the impact of home based exercises on bone mineral density, functional capacity, QoL, and some serological markers of health in HIV infection among Nigerians and South Africans. Methods and design: The study is an assessor-blinded randomized controlled trial. Patients managed with internal and external fixation for femoral shaft fracture at the study sites will be recruited to participate in the study. The participants will be recruited 2 weeks post-discharge at the follow-up clinic with the orthopaedic surgeon. The study population will consist of all persons with femoral fracture and HIV-positive and negative (HIV-positive medically confirmed) aged 18 to 60 years attending the above-named health facilities. For the HIV-positive participants, a documented positive HIV result, as well as a history of being followed-up at the HIV treatment and care center. A developed home based exercise programme will be implemented in the experimental group while the control group continues with the usual rehabilitation programme. The primary outcome measures will be function, gait, bone mineral density, physical activity, and QoL. Discussion: The proposed trial will compare the effect of a home-based physical exercise-training programme in the management of femoral fracture to the usual physiotherapy management programmes with specific outcomes of bone mineral density, function, and inflammatory markers.

Expectancy, usage and acceptance by general practitioners and patients: exploratory results from a study in the German outpatient sector (2017)

Albrecht, Urs-Vito ; Afshar, Kambiz ; Illiger, Kristin ; Becker, Stefan ; Hartz, Tobias ; Breil, Bernhard ; Wichelhaus, Daniel ; von Jan, Ute

Objective: The study’s objective was to assess factors contributing to the use of smart devices by general practitioners (GPs) and patients in the health domain, while specifically addressing the situation in Germany, and to determine whether, and if so, how both groups differ in their perceptions of these technologies. Methods: GPs and patients of resident practices in the Hannover region, Germany, were surveyed between April and June 2014. A total of 412 GPs in this region were invited by email to participate via an electronic survey, with 50 GPs actually doing so (response rate 12.1%). For surveying the patients, eight regional resident practices were visited by study personnel (once each). Every second patient arriving there (inclusion criteria: of age, fluent in German) was asked to take part (paper-based questionnaire). One hundred and seventy patients participated; 15 patients who did not give consent were excluded. Results: The majority of the participating patients (68.2%, 116/170) and GPs (76%, 38/50) owned mobile devices. Of the patients, 49.9% (57/116) already made health-related use of mobile devices; 95% (36/38) of the participating GPs used them in a professional context. For patients, age (P<0.001) and education (P<0.001) were significant factors, but not gender (P>0.99). For doctors, neither age (P¼0.73), professional experience (P>0.99) nor gender (P¼0.19) influenced usage rates. For patients, the primary use case was obtaining health (service)-related information. For GPs, interprofessional communication and retrieving information were in the foreground. There was little app-related interaction between both groups. Conclusions: GPs and patients use smart mobile devices to serve their specific interests. However, the full potentials of mobile technologies for health purposes are not yet being taken advantage of. Doctors as well as other care providers and the patients should work together on exploring and realising the potential benefits of the technology.

Expectancy, usage and acceptance by general practitioners and patients: exploratory results from a study in the German outpatient sector (2017)

Albrecht, Urs-Vito ; Afshar, Kambiz ; Illiger, Kristin ; Becker, Stefan ; Hartz, Tobias ; Breil, Bernhard ; Wichelhaus, Daniel ; von Jan, Ute

Objective The study’s objective was to assess factors contributing to the use of smart devices by general practitioners (GPs) and patients in the health domain, while specifically addressing the situation in Germany, and to determine whether, and if so, how both groups differ in their perceptions of these technologies. Methods GPs and patients of resident practices in the Hannover region, Germany, were surveyed between April and June 2014. A total of 412 GPs in this region were invited by email to participate via an electronic survey, with 50 GPs actually doing so (response rate 12.1%). For surveying the patients, eight regional resident practices were visited by study personnel (once each). Every second patient arriving there (inclusion criteria: of age, fluent in German) was asked to take part (paper-based questionnaire). One hundred and seventy patients participated; 15 patients who did not give consent were excluded. Results The majority of the participating patients (68.2%, 116/170) and GPs (76%, 38/50) owned mobile devices. Of the patients, 49.9% (57/116) already made health-related use of mobile devices; 95% (36/38) of the participating GPs used them in a professional context. For patients, age (P < 0.001) and education (P < 0.001) were significant factors, but not gender (P > 0.99). For doctors, neither age (P = 0.73), professional experience (P > 0.99) nor gender (P = 0.19) influenced usage rates. For patients, the primary use case was obtaining health (service)-related information. For GPs, interprofessional communication and retrieving information were in the foreground. There was little app-related interaction between both groups. Conclusions GPs and patients use smart mobile devices to serve their specific interests. However, the full potentials of mobile technologies for health purposes are not yet being taken advantage of. Doctors as well as other care providers and the patients should work together on exploring and realising the potential benefits of the technology.

On Teaching International Courses on Health Information Systems (2017)

Ammenwerth, Elske ; Knaup, Petra ; Winter, Alfred ; Bauer, Axel W. ; Bott, Oliver J. ; Gietzelt, Matthias ; Haarbrandt, Birger ; Hackl, Werner O. ; Hellrung, Nils ; Hübner-Bloder, Gudrun ; Jahn, Franziska ; Jaspers, Monique W. ; Kutscha, Ulrike ; Machan, Christoph ; Oppermann, Bianca ; Pilz, Jochen ; Schwartze, Jonas ; Seidel, Christoph ; Slot, Jan-Eric ; Smers, Stefan ; Spitalewsky, Katharina ; Steckel, Nathalie ; Strübing, Alexander ; van der Haak, Minne ; Haux, Reinhold ; ter Burg, Willem J.

Background: Health information systems (HIS) are one of the most important areas for biomedical and health informatics. In order to professionally deal with HIS well-educated informaticians are needed. Because of these reasons, in 2001 an international course has been established: The Frank – van Swieten Lectures on Strategic Information Management of Health Information Systems. Objectives: Reporting about the Frank – van Swieten Lectures and about our students‘ feedback on this course during the last 16 years. Summarizing our lessons learned and making recommendations for such international courses on HIS. Methods: The basic concept of the Frank – van Swieten lectures is to teach the theoretical background in local lectures, to organize practical exercises on modelling sub-information systems of the respective local HIS and finally to conduct Joint Three Days as an international meeting were the resulting models are introduced and compared. Results: During the last 16 years, the Universities of Amsterdam, Braunschweig, Heidelberg/Heilbronn, Leipzig as well as UMIT were involved in running this course. Overall, 517 students from these universities participated. Our students‘ feedback was clearly positive. The Joint Three Days of the Frank – van Swieten Lectures, where at the end of the course all students can meet, turned out to be an important component of this course. Based on the last 16 years, we recommend common teaching materials, agreement on equivalent clinical areas for the exercises, support of group building of international student groups, motivation of using a collaboration platform, ensuring quality management of the course, addressing different levels of knowledge of the students, and ensuring sufficient funding for joint activities. Conclusions: Although associated with considerable additional efforts, we can clearly recommend establishing such international courses on HIS, such as the Frank – van Swieten Lectures.

Ontologies for Complex Event Processing (2014)

Astrova, Irina ; Koschel, Arne ; Lukanowski, Jan ; Munoz Martinez, Jose Luis ; Procenko, Valerij ; Schaaf, Marc

In this paper, five ontologies are described, which include the event concepts. The paper provides an overview and comparison of existing event models. The main criteria for comparison are that there should be possibilities to model events with stretch in the time and location and participation of objects; however, there are other factors that should be taken into account as well. The paper also shows an example of using ontologies in complex event processing.

Shopping Cart System: Load Balancing and Fault Tolerance in the OSGi Service Platform (2014)

Astrova, Irina ; Koschel, Arne ; Schneider, Thole ; Westhuis, Johannes ; Westerkamp, Jürgen

The main purpose of this paper was to find a simple solution for load balancing and fault tolerance in OSGi. The challenge was to implement a highly available web application such as a shopping cart system with load balancing and fault tolerance, without having to change the core of OSGi.

OSGi in Cloud Environments (2013)

Astrova, Irina ; Koschel, Arne ; Siekmann, Björn ; Starrach, Mark ; Tebbe, Christopher ; Wolf, Stefan ; Schaaf, Marc

This paper deals with the combination of OSGi and cloud computing. Both technologies are mainly placed in the field of distributed computing. Therefore, it is discussed how different approaches from different institutions work. In addition, the approaches are compared to each other.

Beratung und ihre Ethik : Impulse aus der Beratungskritik und aus Foucaults Philosophie (2019)

Austermann, Frank

In der philosophischen Ethik wird unterschieden zwischen deskriptiver Ethik, normativer Ethik und Metaethik. In diesem Beitrag steht die normative Ethik im Mittelpunkt. Es soll die Frage erörtert werden, welche ethischen Kriterien für die Praxis von Beratung gelten sollten. Zu diesem Zweck werden zunächst beratungskritische Traditionen angeführt und im Anschluss professionsethische Überlegungen mit Rückgriff auf Impulse aus Foucaults Philosophie angestellt.

Ökonomisierung in der Beratung? Zur Notwendigkeit gesellschaftspolitischer Diskurse im Hinblick auf Supervision und Coaching (2015)

Austermann, Frank

Verschriftlichung des Grußworts auf der Fachtagung „Supervision im Suppenküchenstaat - Zur Ökonomisierung der Sozialen Arbeit im Spiegel von Supervision und Coaching“ (Friedberg, 20.10.2014)

Coaching, das Personal entwickelt, Personen ausschließt und Personenentwicklung instrumentalisiert. Ein diskursanalytischer Blick auf Schreyöggs Beratungsverständnis und ihren Rückgriff auf Neubergers "Personalentwicklung" (2013)

Austermann, Frank

Was bedeutet es beratungswissenschaftlich und beratungspraktisch, wenn wie bei Astrid Schreyögg Coaching als Instrument einer Personalentwicklung im Sinne Oswald Neubergers verstanden wird, der ausdrücklich betont: „Der Mensch ist Mittel. Punkt.“ Wie ist ein solches Coachingverständnis diskursanalytisch zuzuordnen, in dem eine bestimmte Arbeits‐ und Organisationspsychologie sich in den Dienst eines bestimmten Verständnisses von Personalwirtschaft stellt? Wie wirkt sich dies in der konkreten Beratungspraxis aus? Welches Menschenbild liegt einem solchen Coaching zugrunde? Lassen sich historisch Modelle rekonstruieren, in denen psychologische Methoden und Techniken im Interesse einer bestimmten ökonomistischen Weltanschauung und Haltung instrumentalisiert wurden? Der Autor vertritt die These, dass „Psychotechnik“ und „Menschenökonomie“ aus den 1910er‐ und 1920er‐Jahren charakteristische Ähnlichkeiten mit einem personalentwicklungsorientierten Coaching aufweisen, wie es Schreyögg unter Rückgriff auf Neubergers Lehrbuch vertritt.

Supervision oder Seelsorge - das ist hier die Frage. Ein diskursanalytischer Diskussionsbeitrag zur pastoralpsychologischen Supervision (2012)

Austermann, Frank

Der Autor setzt sich mit der Frage auseinander, ob pastoralpsychologisch ausgebildete Seelsorger/innen besonders geeignet sind, Mitarbeitende in Kirche und Diakonie zu supervidieren? In der Auseinandersetzung mit Vertretern der pastoralpsychologischen Supervision kommt er zu dem Ergebnis, dass die postulierten Vorteile nur dann zum Tragen kommen, wenn die Supervisoren ihre berufsbezogene Beratungstätigkeit von der theologischen Arbeit zu unterscheiden und zu trennen wissen.

Zu den demokratischen, emanzipatorischen und internationalen Wurzeln der Profession Supervision am Beispiel von Cora Baltussens Beratungsverständnis (2019)

Austermann, Frank

Mit Blick auf Cora Baltussens Leben, Wirken und Beratungsverständnis werden die demokratischen, emanzipatorischen und internationalen Wurzeln der Rezeption der Profession Supervision in Deutschland in den 1950er und 1960er Jahren betont. Das ist besonders notwendig angesichts kritischer Weiterentwicklungen von Supervision und Coaching, bei denen die professionsethischen Grundlagenfragen zum Teil aus dem Blick geraten.

Noise patterns in visceral surgical procedures: Analysis of second-bysecond dBA data of 599 procedures over the course of one year (2020)

Baltin, Christoph Tobias ; Wilhelm, Hendrik ; Wittland, Michael ; Hölscher, Arnulf H. ; Stippel, Dirk ; Astvatsatourov, Anatoli

The objective of this study is to analyze noise patterns during 599 visceral surgical procedures. Considering work-safety regulations, we will identify immanent noise patterns during major visceral surgeries. Increased levels of noise are known to have negative health impacts. Based on a very finegrained data collection over a year, this study will introduce a new procedure for visual representation of intra-surgery noise progression and pave new paths for future research on noise reduction in visceral surgery. Digital decibel sound-level meters were used to record the total noise in three operating theatres in one-second cycles over a year. These data were matched to archival data on surgery characteristics. Because surgeries inherently vary in length, we developed a new procedure to normalize surgery times to run cross-surgery comparisons. Based on this procedure, dBA values were adjusted to each normalized time point. Noise-level patterns are presented for surgeries contingent on important surgery characteristics: 16 different surgery types, operation method, day/night time point and operation complexity (complexity levels 1–3). This serves to cover a wide spectrum of day-to-day surgeries. The noise patterns reveal significant sound level differences of about 1 dBA, with the mostcommon noise level being spread between 55 and 60 dBA. This indicates a sound situation in many of the surgeries studied likely to cause stress in patients and staff. Absolute and relative risks of meeting or exceeding 60 dBA differ considerably across operation types. In conclusion, the study reveals that maximum noise levels of 55 dBA are frequently exceeded during visceral surgical procedures. Especially complex surgeries show, on average, a higher noise exposure. Our findings warrant active noise management for visceral surgery to reduce potential negative impacts of noise on surgical performance and outcome.

Bachelor und Laufbahnbefähigung für den gehobenen Bibliotheksdienst an wissenschaftlichen Bibliotheken – das Eine schließt das Andere nicht aus! (2008)

Behm-Steidel, Gudrun

Der Aufsatz beschäftigt sich mit den Möglichkeiten, die ein Bachelor-Studium im öffentlichen Dienst (gehobene Laufbahn) bietet.

Bestimmung des Kostenverlaufs von Molkereiabteilungen in Abhängigkeit von der Kapazitätsgröße und -auslastung. VI. Teil: Abteilung Betriebsraum (1975)

Behme, Gerhardt

Im Rahmen dieser Veröffentlichungsreihe wird der Kostenverlauf von ausgewählten Molkereiabteilungen in Abhängigkeit von der Kapazitätsgröße und -auslastung ermittelt. Die Bestimmung der Kosten erfolgt mit Hilfe von Modellkalkulationen, deren Daten in umfangreichen Feldanalysen erhoben wurden. Die Grundlage der Verrechnung dieser Daten bildet eine spezielle Form der Teilkostenrechnung.

Bestimmung des Kostenverlaufs von Molkereiabteilungen in Abhängigkeit von der Kapazitätsgröße und -auslastung. IV. Teil: H-Milch-Abteilung (1975)

Behme, Gerhardt

Es werden die Kosten der H-Milchabteilung bei drei verschiedenen Kapazitätsgrößen mit jeweils variierter Kapazitätsauslastung nach einer speziellen Form der Teilkostenrechnung bestimmt. Die Kapazitätsgrößen betragen 3300, 6600 und 9900 1-l-Packungen pro Stunde. Im Jahr werden zwischen 2,9 und 53,6 Mio. Einheiten hergestellt; dabei variieren die Stückkosten zwischen 30,65 und 18,85 Pf/1-l-Packung. Es zeigt sich dabei, daß die Kostendegression entscheidend stärker durch den Grad der Kapazitätsauslastung als durch die Kapazitätsgröße beeinflußt wird.

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