Refine
Year of publication
Document Type
- Article (47)
Language
- English (47)
Has Fulltext
- yes (47)
Is part of the Bibliography
- no (47)
Keywords
- Student (10)
- India (8)
- Knowledge (8)
- Mumbai (8)
- Wissen (8)
- Indien (6)
- University students (6)
- Antibiotikum (5)
- HIV (5)
- Antibiotic resistance (4)
- Klinisches Experiment (4)
- Pakistan (4)
- clinical research (4)
- Arzneimittelresistenz (3)
- Attitude (3)
- Karachi (3)
- Pharmaziestudent (3)
- USA (3)
- African socio-cultural context (2)
- Afrika (2)
- Aids (2)
- Antibiotic (2)
- Antibiotics (2)
- Diabetes mellitus (2)
- Einstellung (2)
- Karatschi (2)
- Lebensqualität (2)
- Mumbai, India (2)
- Mundhöhlenkrebs (2)
- Nigeria (2)
- Oral cancer (2)
- Pharmacy (2)
- Rauchen (2)
- Selbstmedikation (2)
- Self-medication (2)
- Smoking (2)
- Students (2)
- Tabakkonsum (2)
- Tobacco (2)
- cost-effectiveness (2)
- developing countries (2)
- modifiable characteristics of the vulnerable patients (2)
- Adult Vaccines (1)
- Adverse drug event (1)
- Adverse drug reaction (1)
- Aerobes Training (1)
- Aerobic exercise (1)
- African countries (1)
- Antidiabetic (1)
- Antidiabetikum (1)
- Antiretroviral therapy (1)
- App <Programm> (1)
- Approval (1)
- Approvals (1)
- Arzneimittel (1)
- Arzneimittelnebenwirkung (1)
- Arzneimittelüberwachung (1)
- Automobile spray painters (1)
- Awareness (1)
- Berufskrankheit (1)
- Bewegungstherapie (1)
- Blutspende (1)
- CD4+ cell count (1)
- Cardiorespiratory function (1)
- Cell phone (1)
- Cement workers (1)
- Childhood febrile conditions (1)
- Chronische Niereninsuffizienz (1)
- Cleaners (1)
- Clinical Trials (1)
- Clinical trial (1)
- Communication (1)
- Community-dwelling older adults (1)
- Cost-effectiveness (1)
- DALY (1)
- Data quality control (1)
- Datenqualität (1)
- Declaration of Helsinki (1)
- Depression (1)
- Developing Countries (1)
- Diabetes mellitus Typ 2 (1)
- Diabetic wound healing (1)
- Discriminatory power (1)
- Disease Burden (1)
- Disease burden (1)
- Drogenmissbrauch (1)
- E-cadherin (1)
- Ebola-Virus (1)
- Economic and political/governmental infrastructural factors (1)
- Education (1)
- Educational intervention (1)
- Effizienz (1)
- Entscheidungsfindung (1)
- Entwicklungsländer (1)
- Epilepsie (1)
- Epilepsy (1)
- European Union (1)
- Exercise training (1)
- Fahrzeuglackierer (1)
- Falls (1)
- Fraktionierung (1)
- Genehmigung (1)
- Germany (1)
- Gesundheitswesen (1)
- Grand mean (1)
- HAART (1)
- HIV-Infektion (1)
- HIV/AIDS (1)
- HPV (1)
- Haematological parameters (1)
- Handy (1)
- Health services (1)
- Heil- und Hilfsmittel (1)
- Holzarbeiter (1)
- Humanes Papillomavirus (1)
- Hygiene (1)
- ICH-GCP (1)
- Impfstoff (1)
- Impfung (1)
- Income (1)
- Indonesia (1)
- Infrastruktur (1)
- Kardiopulmonale Leistungsfähigkeit (1)
- Knochenbruch (1)
- Knochendichte (1)
- Krafttraining (1)
- Krampf (1)
- Krankenhaus (1)
- Körperliche Leistungsfähigkeit (1)
- Luftqualität (1)
- Ländlicher Raum (1)
- Maharashtra (1)
- Matunga (1)
- Mechanism (1)
- Medical Ethics (1)
- Medical devices (1)
- Medical expertise (1)
- Medication adherence (1)
- Mental health (1)
- Metaanalyse (1)
- Mitigation plan (1)
- Monitoring (1)
- Mothers’ perception of recovery (1)
- Mothers’ satisfaction (1)
- Multicenter clinical trials (1)
- Nanomedicine (1)
- Nanotechnology (1)
- Nanotoxicity (1)
- Occupational-specific variations (1)
- Osteoporose (1)
- Patent medicine dealers (1)
- Patient (1)
- Patient satisfaction (1)
- Perception (1)
- Pharmacists (1)
- Pharmacovigilance (1)
- Pharmazeut (1)
- Pharmazeutische Industrie (1)
- Pharmazie (1)
- Physical activity level (1)
- Physical exercise adherence (1)
- Physikalische Therapie (1)
- Physiotherapeut (1)
- Piper crocatum Ruiz & Pav (1)
- Poststroke depression (1)
- Psychische Gesundheit (1)
- Quality of Life (1)
- Quality of life (1)
- Raigad (1)
- Rational drug use (1)
- Registrierung (1)
- Registry data (1)
- Regulations (1)
- Reliability (1)
- Resistance (1)
- Resistance exercise (1)
- Resistenz (1)
- Risikoanalyse (1)
- Risk methodology assessment (1)
- Risk-based monitoring (1)
- Rural community (1)
- SMS <Telekommunikation> (1)
- SOD1 (1)
- Schlaganfallpatient (1)
- Schulung (1)
- Seizures (1)
- Selbstmanagement (1)
- Social participation (1)
- Spanien (1)
- Stadt (1)
- Sturz (1)
- Symptom (1)
- Symptoms of post-stroke depression (1)
- Systematic review (1)
- Tala (1)
- Teilhabe (1)
- Text-message (1)
- Therapietreue (1)
- Timed-up-and-go test (1)
- USFDA (1)
- Unerwünschte Arzneimittelwirkung (1)
- University Students (1)
- Vaccine (1)
- Validity (1)
- Velocity field diagram (1)
- Voluntary blood donation (1)
- Woodworkers (1)
- Wundheilung (1)
- Yogyakarta (1)
- Zufriedenheit (1)
- adult vaccines (1)
- antidiabetic (1)
- antihypertensive (1)
- belief (1)
- bioethics (1)
- biomedicine (1)
- bone mineral density (1)
- chronic kidney disease (1)
- clinical trial (1)
- clinical trials (1)
- culture (1)
- data protection (1)
- dentist (1)
- developing country (1)
- diabetes mellitus (1)
- education (1)
- ethnomedicine (1)
- fracture (1)
- healing (1)
- healthcare systems (1)
- hypertension (1)
- income (1)
- medical data (1)
- medicine registrations (1)
- meta-analysis (1)
- mobile health apps (1)
- musculoskeletal disorders, (1)
- non-prescription (1)
- occupational disorders (1)
- osteoporosis (1)
- p53 (1)
- performance of the pharmaceutical industry (1)
- placebo (1)
- questionnaire (1)
- roads to health (1)
- self-management (1)
- self-medication (1)
- self-prescription (1)
- standard of care (1)
- survey (1)
- symptoms of post-stroke depression (1)
- university students (1)
- Älterer Mensch (1)
Institute
The drugs we use to treat any condition – from an innocuous cough to a life-threatening cancer – are the outcome of painstaking human clinical trials. These trials are the only way to credibly determine the safety and efficacy of drugs. In recent years there has been a clear shift in clinical trial sites from core developed countries like USA, European countries to developing countries like India, China, South American countries. This shift is related to challenges and opportunities like costs of trials, recruitment issues, and regulatory challenges in developed vs. developing countries. Developing countries and developed countries have their unique disease burden patterns based on various parameters like but not limited to age, health care facilities, health insurance, sanitary conditions, environmental issues, education, nutrition
and GDP. Previous studies have reported that many of the important global diseases are not much explored in clinical trials and many published clinical trials have very less international health relevance. This study was aimed at finding the correlation between disease burdens, number of clinical trials done and trial success rates. We compared 2005 - 2010 Global Burden of Disease data for Germany, India and number of clinical trials from clinicaltrials.gov database done in the same period. Our findings indicated that there was a good correlation between the disease burden and clinical trials for Germany in 2005 and 2010. For India in 2005 there was a moderate positive correlation, 2010 data showed the improvement in India in terms of match between disease burden and clinical trials. But careful observation of the data shows still a need for more trials on Communicable, maternal, neonatal and nutritional disorders.