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Clinical Research and Standard of Care — An Unresolved Question?

  • Ever since the 1996 revision of the Declaration of Helsinki, the World Medical Association has attempted to address ethical and scientific concerns of its diverse stakeholders for Articles 33 (use of placebo) and 34 (posttrial provisions), most recently in 2013. Both are inextricably linked to standard of care, an essential element of any comparative, interventional clinical trial. But has this now 20-year-long ethical debate truly been put to rest? The choice of standard of care in clinical trials remains a complex issue, particularly for comparative trials conducted in emerging countries.

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Metadaten
Author:Nadia Tornieporth, Firas Fneish, Gerhard FortwengelORCiDGND
URN:urn:nbn:de:bsz:960-opus4-9113
DOI:https://doi.org/10.1016/j.curtheres.2016.05.011
Parent Title (English):Current Therapeutic Research
Document Type:Article
Language:English
Release Date:2016/07/13
Tag:Declaration of Helsinki; bioethics; clinical research; placebo; standard of care
Volume:78
Issue:Supplement
First Page:S4
Last Page:S5
Link to catalogue:1684838746
Institutes:Fakultät III - Medien, Information und Design
DDC classes:610 Medizin, Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung 4.0