TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed)
A1  - Tornieporth, Nadia
A1  - Fneish, Firas
A1  - Fortwengel, Gerhard
T1  - Clinical Research and Standard of Care — An Unresolved Question?
JF  - Current Therapeutic Research
N2  - Ever since the 1996 revision of the Declaration of Helsinki, the World Medical Association has attempted to address ethical and scientific concerns of its diverse stakeholders for Articles 33 (use of placebo) and 34 (posttrial provisions), most recently in 2013. Both are inextricably linked to standard of care, an essential element of any comparative, interventional clinical trial. But has this now 20-year-long ethical debate truly been put to rest? The choice of standard of care in clinical trials remains a complex issue, particularly for comparative trials conducted in emerging countries.
KW  - bioethics
KW  - clinical research
KW  - Declaration of Helsinki
KW  - placebo
KW  - standard of care
Y1  - 2016
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:960-opus4-9113
U6  - https://doi.org/10.1016/j.curtheres.2016.05.011
DO  - https://doi.org/10.1016/j.curtheres.2016.05.011
VL  - 78
IS  - Supplement
SP  - S4
EP  - S5
ER  -