TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed)
A1  - Titze, Isabel
A1  - Krömker, Volker
T1  - Antimicrobial Activity of a Phage Mixture and a Lactic Acid Bacterium against Staphylococcus aureus from Bovine Mastitis
JF  - Veterinary Sciences
N2  - The antimicrobial activity of a phagemixture and a lactic acid bacteriumagainst Staphylococcus aureus isolates from bovine origin was investigated in vitro with regard to possible applications in the therapy of udder inflammation (mastitis) caused by bacterial infections. The S. aureus isolates used for inoculation derived from quarter foremilk samples of mastitis cases. For the examination of the antimicrobial activity, the reduction of the S. aureus germ density was determined [log10 cfu/mL]. The phage mixture consisted of the three obligatory lytic and S. aureus-specific phages STA1.ST29, EB1.ST11 and EB1.ST27 (1:1:1). The selected Lactobacillus plantarum strain with proven antimicrobial properties and the phage mixture were tested against S. aureus in milk, both alone and in combination. The application of the lactic acid bacterium showed only a low reduction ability for a 24 h incubation period. The bacteriophage mixture as well as its combination with the lactic acid bacterium showed high antimicrobial activity against S. aureus for a 24 h incubation period at 37 � C, with only the phage mixture showing significance.
KW  - bacteriophage mixture
KW  - Staphylococcus aureus
KW  - Bakteriophagen
KW  - Therapie
KW  - Euterentzündung
KW  - Rind
KW  - phage therapy
KW  - lytic phage
KW  - lactic acid bacterium
KW  - dairy
KW  - bovine mastitis
Y1  - 2020
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:960-opus4-16384
SN  - 2306-7381
SS  - 2306-7381
U6  - https://doi.org/10.25968/opus-1638
DO  - https://doi.org/10.25968/opus-1638
VL  - 7
IS  - 1
PB  - MDPI
ER  -