TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Crowder, Sylvia L. A1 - Playdon, Mary C. A1 - Gudenkauf, Lisa M. A1 - Ose, Jennifer A1 - Gigic, Biljana A1 - Greathouse, Leigh A1 - Peoples, Anita R. A1 - Sleight, Alix G. A1 - Jim, Heather S. L. A1 - Figueiredo, Jane C. T1 - A Molecular Approach to Understanding the Role of Diet in Cancer-Related Fatigue: Challenges and Future Opportunities JF - Nutrients N2 - Cancer-related fatigue (CRF) is considered one of the most frequent and distressing symptoms for cancer survivors. Despite its high prevalence, factors that predispose, precipitate, and perpetuate CRF are poorly understood. Emerging research focuses on cancer and treatment-related nutritional complications, changes in body composition, and nutritional deficiencies that can compound CRF. Nutritional metabolomics, the novel study of diet-related metabolites in cells, tissues, and biofluids, offers a promising tool to further address these research gaps. In this position paper, we examine CRF risk factors, summarize metabolomics studies of CRF, outline dietary recommendations for the prevention and management of CRF in cancer survivorship, and identify knowledge gaps and challenges in applying nutritional metabolomics to understand dietary contributions to CRF over the cancer survivorship trajectory. KW - metabolomics KW - diet-related disease KW - dietary intervention KW - cancer survivors KW - nutrition KW - Metabolomik KW - Ernährungskrankheit KW - Ernährung KW - Erschöpfung Y1 - 2022 UN - https://nbn-resolving.org/urn:nbn:de:bsz:960-opus4-31636 SN - 2072-6643 SS - 2072-6643 U6 - https://doi.org/10.25968/opus-3163 DO - https://doi.org/10.25968/opus-3163 VL - 14 IS - 7 SP - 14 S1 - 14 PB - MDPI ER -